South Africa’s recently published guidelines for the treatment of tuberculosis (TB) infection have been welcomed by several experts. Among others, the guidelines endorse the use of a three-month course of TB preventive therapy as opposed to the old six-month course. But, while the intention is to roll out the three-month course quite widely, supply constraints may delay things. Tiyese Jeranji reports.
New tuberculosis infection guidelines released ahead of World TB Day are another important step in the right direction for South Africa’s TB response, argues Spotlight editor Marcus Low, while also warning of the substantial implementation challenges that remain.
The uptake and continuation of tuberculosis preventive therapy were much higher when it was provided through a community-based model compared to the standard clinic-based model, a study conducted in KwaZulu-Natal found. Elri Voigt unpacks the study findings, which were recently presented at the Conference for Retroviruses and Opportunistic Infections in Seattle, USA.
The current treatment for drug-susceptible tuberculosis (TB) used in South Africa last for six months, effectively cures TB and is dirt cheap. Two studies in recent years have shown that TB can be cured in four or in some cases even two months, but price and other complications make these treatments tricky to implement. At a conference in Seattle last week, a major trial of an alternative four-month treatment reported disappointing findings. Elri Voigt unpacks the latest findings and asks what the prospects now are for shortening TB treatment.
According to the World Health Organization, of the roughly 10 million people who fall ill with TB annually, over 80% survive, in most cases due to a six-month treatment course. Unfortunately, as with long COVID, being cured is not always the last hurdle and many people go on to struggle with post-TB lung disease. Tiyese Jeranji asked local experts about this sometimes-neglected area of TB care.
The Mpumalanga Health Department plans to repurpose three TB hospitals due to dwindling numbers of in-patients at these hospitals. The hospitals – Bongani TB Hospital, Standerton TB Hospital, and Barberton TB Hospital – will be used for other health services. Nthusang Lefafa asked the department what prompted this and what it means for the TB response in the province.
2023 is set to be another tumultuous year for healthcare services, health policy, and governance in South Africa. We’ve picked 13 things to look out for this year arranged under three broad headings: leadership and governance, policy and legislation, and HIV, TB and the NSP.
Health budgets have the power to advance access to healthcare for millions of people in South Africa. This year, however, as the health sector and the economy recovered from the worst of the COVID-19 pandemic and a volatile global environment, the South African government missed opportunities to provide the financial resources to protect access to healthcare for the most vulnerable. Matshidiso Lencoasa unpacks how the past year’s budget choices will affect key public health services.
South Africa’s National Department of Health is set to receive a donation of child-friendly formulations of several medicines used to treat drug-resistant tuberculosis (DR-TB). It is expected that over the next year the donation will spare roughly 200 children the substantial difficulties associated with taking DR-TB medicines meant for adults.
An HIV prevention injection approved in South Africa, several promising developments on the tuberculosis front, the National Health Insurance Bill grinding its way through Parliament, no end in sight to healthcare worker shortages, another dire year for health in Gauteng – Spotlight wraps up 2022 in under 1 000 words.
Diagnosing tuberculosis is difficult in people who struggle to cough up sputum samples – a particular problem in children and people living with HIV. One promising alternative to testing sputum is to test stool. Tiyese Jeranji unpacks the latest developments in this area.
Falling ill with tuberculosis (TB) can be challenging for anyone, but it can be especially hard if you are pregnant or have just given birth. Globally, TB is amongst the top five causes of death in women of childbearing age. Tiyese Jeranji spoke to experts about the risks, challenges, and ongoing studies on maternal TB.