TB treatment can be cut to two months for some, finds landmark study

TB treatment can be cut to two months for some, finds landmark study

Some cases of tuberculosis (TB) can be successfully treated in as little as two months – a third of the current standard of six months. This is according to early findings from the landmark TRUNCATE TB trial presented at last week’s Union World Conference on Lung Health. Elri Voigt reports.

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In-depth: Major SAMRC study sheds light on causes of disease and death in SA

In-depth: Major SAMRC study sheds light on causes of disease and death in SA

Unsafe sex, interpersonal violence, high body mass index, high systolic blood pressure, and alcohol consumption are the top risk factors for disease and death in South Africa, according to the Second Comparative Risk Assessment study conducted by the South African Medical Research Council’s Burden of Disease Research Unit. Nthusang Lefafa spoke to some of the researchers to unpack the findings.

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56 000 TB deaths in SA in 2021, estimates WHO

56 000 TB deaths in SA in 2021, estimates WHO

In 2021, an estimated 304 000 people in South Africa fell ill with tuberculosis and 56 000 died from the disease, according to new World Health Organization (WHO) figures released on Thursday. Elri Voigt unpacks the latest findings and asks local experts for their responses.

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Digital X-rays boosting TB diagnosis, assessment finds

Digital X-rays boosting TB diagnosis, assessment finds

Many people with tuberculosis (TB) in South Africa are never diagnosed or are diagnosed only once their symptoms have become quite severe. One solution to diagnosing more people more quickly is the expanded use of new digital X-ray technology. Now, an independent assessment of digital X-ray pilot projects in six districts in South Africa sheds light on how well this intervention works in the real world. Tiyese Jeranji reports.

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In-depth: The complex relationship between TB and mental health

In-depth: The complex relationship between TB and mental health

Tuberculosis (TB) disease and all the disruption and stress that goes along with it can take a toll on someone’s mental health, and mental health problems can in turn make someone more vulnerable to TB. In the wake of World Mental Health Day 2022, Tiyese Jeranji explores the complex links between mental health and TB.

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INTERVIEW: Prof Wendy Stevens on following the science, even if it means swimming against the stream

INTERVIEW: Prof Wendy Stevens on following the science, even if it means swimming against the stream

Professor Wendy Stevens believes ‘completely in the honesty of science’ and this, she says, has landed her in the naughty corner many times throughout her career. Biénne Huisman spoke to Stevens – a global leader in HIV and TB laboratory medicine about her career, what you choose when science and politics collide, and the value of swimming upstream.

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In-depth: Use of urine test for TB increasing

In-depth: Use of urine test for TB increasing

In 2015, the World Health Organization recommended a urine test that helps with the detection of tuberculosis (TB) in people living with HIV who are hospitalised or who have compromised immune systems. While uptake of this test in South Africa was initially quite slow, numbers presented at the recent South African TB Conference suggest that the use of the test is now increasing. Tiyese Jeranji reports.

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From Cameroonian village to Stellenbosch Professor – top TB researcher reflects on a remarkable journey

From Cameroonian village to Stellenbosch Professor – top TB researcher reflects on a remarkable journey

When Novel Chegou first arrived in Stellenbosch from Cameroon in 2004 he sold African crafts at a stall next to the town’s village green to save money for his studies. Today, Professor Chegou is one of South Africa’s leading tuberculosis researchers. Biénne Huisman caught up with Chegou shortly after the announcement that he had been awarded the Royal Society Africa Prize.

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TB treatment to be shortened to 4 months for most kids

TB treatment to be shortened to 4 months for most kids

South Africa last published comprehensive guidelines for the management of childhood tuberculosis (TB) in 2013. Almost a decade later, the guidelines are being updated to recommend a shortened TB treatment regimen for most children with pulmonary TB. Catherine Tomlinson reports.

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As testing volumes improve, government outlines TB recovery plan

As testing volumes improve, government outlines TB recovery plan

South Africa’s tuberculosis (TB) testing numbers have recovered from dramatic declines in 2020, delegates heard at the opening of the 7th South African TB Conference in Durban. The Department of Health also provided some details of its TB recovery plans and targets. Tiyese Jeranji reports from Durban.

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Experts weigh in on the potential of ultrasound for diagnosing TB in kids

Experts weigh in on the potential of ultrasound for diagnosing TB in kids

Tuberculosis can be challenging to diagnose in children, especially very young children. This is because it is difficult for them to cough up the sputum required by gold standard molecular tests and because they have fewer TB organisms in their sputum than adults. X-ray screening may be part of the solution, but it has shortcomings. Following some interesting recent study findings, Tiyese Jeranji asks what role lung ultrasound may have in improving TB detection in kids.

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Shorter, simpler DR-TB regimen expected later this year

Shorter, simpler DR-TB regimen expected later this year

A new six-month treatment regimen for drug-resistant forms of tuberculosis is expected to be rolled out in the public sector later this year – current regimens take anything from nine to 18 months. Catherine Tomlinson unpacks why the switch is important and outlines what still needs to happen to make it a reality.

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