Analysis: SA close to meeting TB research funding targets, but most countries falling short

South Africa is one of only six countries to ever meet their “fair share target” for funding tuberculosis (TB) research, according to a new report. In absolute terms however, South Africa’s contribution is small change compared to investments into TB research made by the top two contributors, the United States government and the Bill and Melinda Gates Foundation. Catherine Tomlinson unpacks what the report tells us about investment in TB research in South Africa.

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INTERVIEW: Prof Wendy Stevens on following the science, even if it means swimming against the stream

Professor Wendy Stevens believes ‘completely in the honesty of science’ and this, she says, has landed her in the naughty corner many times throughout her career. Biénne Huisman spoke to Stevens – a global leader in HIV and TB laboratory medicine about her career, what you choose when science and politics collide, and the value of swimming upstream.

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Positive signs for new TB testing strategy

Under a new tuberculosis (TB) diagnosis strategy, people considered to be at high risk of TB are offered molecular TB tests, even if they do not have any symptoms. A landmark study in 2020 showed that such a strategy can help diagnose more people more quickly. Now, early indications are that it also works in the real world and South Africa’s lab service says they can cope with the increased demand. Tiyese Jeranji reports.

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Analysis: Is SA on course to solve its TB diagnosis problem?

It is estimated that over 100 000 of the over 300 000 people who fall ill with TB in South Africa every year are not diagnosed. As a result, improving TB screening and testing has become a high priority in South Africa’s TB response. Coinciding with World TB Day 2022, Spotlight editor Marcus Low examines new information shared by the National Department of Health and assesses the state of the country’s TB case-finding efforts.

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COVID-19: What tests are available in SA and which ones to use?

The different types of COVID-19 tests are far from equal. Picking a test is generally a matter of speed versus accuracy and, most importantly, why you need a test and when. What are the limitations of these tests? Is there any quality control? What are the chances of false positives and false negatives? Elsabé Brits surveys the landscape of tests available in South Africa and asks which type is most appropriate in what situation.

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COVID-19: NHLS reducing its dependence on “a few suppliers”

Early enthusiasm about South Africa’s strong position to scale up COVID-19 testing due to existing investments in diagnostic infrastructure for HIV and TB waned after the country found itself unable to secure adequate test materials. Steps are now being taken to reduce the dependence on just a few suppliers for these materials. Catherine Tomlinson reports.

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