Researchers have been trying to develop antiretroviral medicines that can last for weeks, months or even years per dose. Two such long-acting formulations have been approved in South Africa, but several more are on the horizon. Elri Voigt explores the science behind what makes a formulation long-acting and takes a look at some particularly exciting prospects.
During the COVID-19 pandemic, we saw the remarkable power of genomics in helping us keep track of new viral variants. Several scientists argue that Africa should continue to invest in genomics to support disease control and public health. Sue Segar asks what this means in practice and why it is considered so critically important.
South Africa’s National Strategic Plan for HIV, TB and STIs (2023 – 2028) was launched on Friday at Tlhabane Stadium in Rustenburg, North West as the world commemorated World TB Day. Nthusang Lefafa attended the event and spoke to experts and activists about the state of TB and HIV and the work that lies ahead with the new NSP.
A vaginal ring used to prevent HIV infection is safe to use during late pregnancy and while breastfeeding, according to findings presented at a major international HIV conference in Seattle in the United States. The news comes as South Africa prepares for a likely national rollout of the ring and as more research confirms the safety of an HIV prevention pill during pregnancy. It is estimated that offering these products to pregnant and breastfeeding women could avert up to 136 000 new infections in roughly the next decade. Laura Lopez Gonzalez reports.
Despite some improvement, the community-led monitoring group Ritshidze’s second report on key populations highlights that sex workers, people who use drugs and LGBTQIA+ community members are often still discriminated against when trying to access public health facilities. This can lead to treatment interruptions and some stopping their clinic visits. Nthusang Lefafa reports.
A study published last year on an HIV variant that has been circulating in the Netherlands for the last 20 years reminded the public of the existence of viral variants beyond SARS-CoV-2. Elri Voigt unpacks what we know about the HI-virus, its variants, and the study’s findings.
South Africa’s HIV testing programme has been a huge success over the last decade, largely due to the use of rapid tests. Now, the introduction of a new generation of rapid tests may offer some benefits over the current tests, but the picture is somewhat complicated and the Department of Health is not currently planning to use the new tests. Amy Green investigates.
In December 2022, the Minister of Justice, Ronald Lamola, set into motion a public participation process on the laws that govern sex work in South Africa. Marlise Richter & Pamela Chakuvinga point out that while the Bill published for public comment in December is very short, it will do something quite extraordinary if it does become law – it will fully decriminalise sex work. This, they argue, is a process we must see through.
Antibiotics play a vital role in the management of bacterial infections, reducing illness, and preventing many deaths. A 2011 report from the UK estimated that they have increased life expectancy by 20 years. However, the extensive use of antibiotics has resulted in drug resistance that threatens to reverse their life-saving power and if the situation is not reversed, it has been estimated that by 2050 as many as 10 million people will die annually of drug-resistant infections. Tiyese Jeranji looks at how antimicrobial resistance plays out in South Africa and the role of pharmacists in the fight against it.
KwaZulu-Natal clinics are outperforming facilities monitored in other provinces on various indicators and health services in the province have improved year-on-year, but some marginalised groups continue to have a hard time accessing healthcare services. This is according to the latest provincial report from community-led monitoring project Ritshidze. Nthusang Lefafa spoke to several NGOs about the findings and asked the province’s health department for their response.
Professor Wendy Stevens believes ‘completely in the honesty of science’ and this, she says, has landed her in the naughty corner many times throughout her career. Biénne Huisman spoke to Stevens – a global leader in HIV and TB laboratory medicine about her career, what you choose when science and politics collide, and the value of swimming upstream.
When Novel Chegou first arrived in Stellenbosch from Cameroon in 2004 he sold African crafts at a stall next to the town’s village green to save money for his studies. Today, Professor Chegou is one of South Africa’s leading tuberculosis researchers. Biénne Huisman caught up with Chegou shortly after the announcement that he had been awarded the Royal Society Africa Prize.
