Around 7.8 million people were living with HIV in South Africa in 2022, of which 5.7 million were taking antiretroviral treatment. Currently, HIV treatment is life-long, something that makes treatment adherence challenging for some. Tiyese Jeranji explores what role Digital Adherence Technologies can play in helping people stay on treatment.
Last year, Spotlight reported that taking a widely available antibiotic, doxycycline after condomless sex can reduce the risk of contracting three different sexually transmitted infections (STIs). Elri Voigt unpacks some further results from three studies presented at CROI2023 on Doxycycline as post-exposure prophylaxis (PEP) for STI prevention.
The current treatment for drug-susceptible tuberculosis (TB) used in South Africa last for six months, effectively cures TB and is dirt cheap. Two studies in recent years have shown that TB can be cured in four or in some cases even two months, but price and other complications make these treatments tricky to implement. At a conference in Seattle last week, a major trial of an alternative four-month treatment reported disappointing findings. Elri Voigt unpacks the latest findings and asks what the prospects now are for shortening TB treatment.
New research shows a quick-dissolving, rectal suppository designed to prevent HIV infection is safe, although its efficacy remains to be tested in clinical trials, some of which will be conducted in South Africa. Still, the findings released late Tuesday could herald the start of a new “take as needed” era in HIV prevention.
A vaginal ring used to prevent HIV infection is safe to use during late pregnancy and while breastfeeding, according to findings presented at a major international HIV conference in Seattle in the United States. The news comes as South Africa prepares for a likely national rollout of the ring and as more research confirms the safety of an HIV prevention pill during pregnancy. It is estimated that offering these products to pregnant and breastfeeding women could avert up to 136 000 new infections in roughly the next decade. Laura Lopez Gonzalez reports.