It has been a bruising year or so for medical researchers in South Africa with the US pausing, cancelling, and then resuming some grants. But as bad as things were, what played out wasn’t the worst case scenario, and momentum is now building toward recovery.
Soft toys, giggly kisses, and bright wards buzzing with excited children meet a driven team of staff and researchers producing world class work at Brooklyn Chest Hospital’s paediatric TB research hub. Biénne Huisman visits the wards and the Desmond Tutu TB Centre’s clinical site as it celebrates ten years and gets early insight of a cutting-edge new treatment trial.
Although TB can be cured, it is still spreading in South Africa at alarming rates. One reason could be that some people with TB disease but without TB symptoms may unknowingly be passing on the bug. In this Spotlight special briefing, Elri Voigt unpacks what we do and do not know about asymptomatic TB.
The wins are there but the underlying reality remains, writes Professor Kogie Naidoo as she likens TB to a bridesmaid awaiting its turn to garner attention. The analogy is relevant given the overwhelming number of new TB infections and deaths each year globally for a disease persistently sitting in the shadow of other communicable and non-communicable diseases.
New TB tests have massive potential for South Africa’s struggle to get to grips with the age-old disease. Making the most of these new tests will require both ambition and smart implementation, argue Gaurang Tanna and Dr Yogan Pillay.
The persistence of TB is a reminder that medical solutions alone are not enough. Renier Coetzee and Ingrid Schoeman write that the disease thrives in conditions shaped by social injustice, including poverty, overcrowded housing, under-resourced health systems, and unequal access to care.
The only tuberculosis vaccine we have is a century old and offers only limited efficacy in children. With leading South African researchers involved in the pivotal clinical trials of three new tuberculosis vaccine candidates, we are on the verge of a major breakthrough, writes Associate Professor Angelique Kany Kany Luabeya.
The new government TB dashboard is a step forward for transparency and accountability in South Africa’s response to the ancient, but still deadly, disease. It is critical that we use it wisely to boost our testing efforts, argues a group of South Africa’s leading TB activists ahead of World TB Day on March 24th.
Funding cuts over the last year or so have created a crisis for multilateral health institutions. Which institutions emerge from this crisis, and in what form, will have real consequences for the health of people in South Africa, argues Spotlight editor Marcus Low.
Spotlight has unveiled a new tuberculosis dashboard and graph generator. We hope this dashboard will help people get a clearer picture of the state of South Africa’s TB epidemic – an epidemic that still claims over 50 000 lives a year. It follows on the launch of a similar HIV dashboard last November.
From the limited rollout of a new HIV prevention jab to developments with new weight loss medicines, to high-stakes court cases relating to National Health Insurance (NHI), 2026 is set to be another tumultuous year in healthcare. Here are nine stories that Spotlight will keep a close eye on.
South Africa had several “family chats” in which President Cyril Ramaphosa addressed the nation during the height of the COVID-19 pandemic. He should do the same for tuberculosis, argues Dr Janet Giddy of the advocacy group TB Proof.
