What we can learn about TB at the autopsy table

What we can learn about TB at the autopsy table

In addition to shedding light on what people actually die of, autopsies can also play an important role in helping us to better understand disease. Tiyese Jeranji unpacks tuberculosis-related autopsy research in the Western Cape and delves into some of the fascinating complexities of this branch of TB research.

Read More

‘Let’s unite to end TB’ – a community-led approach can help wipe out TB in SA

‘Let’s unite to end TB’ – a community-led approach can help wipe out TB in SA

World TB Day is marked in the same week that South Africa celebrates Human Rights Day. A human rights based approach to TB mirrors a public health approach, argue Ingrid Schoeman, Sasha Stevenson, Janet Giddy, Renier Coetzee, and Petula Pienaar.

Read More

New TB drug shows promise, but experimental vaccine disappoints

New TB drug shows promise, but experimental vaccine disappoints

While three new tuberculosis (TB) medicines have been registered in South Africa over the last decade, TB treatment still comes with several side effects and requires taking multiple different medicines, typically for six or more months. The search for better TB medicines got a boost last week with the presentation of promising findings from a study conducted in South Africa on an experimental drug called quabodepistat. Elri Voigt reports on this and other TB studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Denver, Colorado.

Read More

EDITORIAL: With elections and NHI, this is a big year for healthcare in SA

EDITORIAL: With elections and NHI, this is a big year for healthcare in SA

South Africa is barrelling towards its most consequential and most competitive national and provincial elections since 1994. Spotlight editor Marcus Low asks what is on the line in these elections from a healthcare perspective and argues that the stakes are particularly high when it comes to NHI and the Gauteng and KwaZulu-Natal provincial health departments.

Read More

Analysis: SA close to meeting TB research funding targets, but most countries falling short

Analysis: SA close to meeting TB research funding targets, but most countries falling short

South Africa is one of only six countries to ever meet their “fair share target” for funding tuberculosis (TB) research, according to a new report. In absolute terms however, South Africa’s contribution is small change compared to investments into TB research made by the top two contributors, the United States government and the Bill and Melinda Gates Foundation. Catherine Tomlinson unpacks what the report tells us about investment in TB research in South Africa.

Read More

Antibiotic slashes risk of drug-resistant TB in kids, finds major SA study

Antibiotic slashes risk of drug-resistant TB in kids, finds major SA study

Tuberculosis (TB) preventive therapy has been transformed in recent years, with treatment duration having been cut from six or more months to just three or one. Progress in developing new treatments to prevent drug-resistant forms of TB has however lagged behind, especially in children. Elri Voigt unpacks findings from a major new TB prevention study presented at the Union World Conference on Lung Health last week and plans for another important preventive therapy trial set to start soon.

Read More

Interview: “Someone had to do it”, says SA TB activist on Time 100 list

Interview: “Someone had to do it”, says SA TB activist on Time 100 list

At the age of 19 Phumeza Tisile contracted multidrug-resistant tuberculosis. For four years she battled the disease, losing her hearing in the process. At one stage, a doctor told her to visit a priest and prepare her soul for death. Recently, Tisile (now 33) made it on to TIME magazine’s 2023 TIME100 Next list, as one of 100 emerging leaders round the world who are “shaping the future and defining the next generation of leadership”. Sue Segar chatted to Tisile about her remarkable journey.

Read More

Interview: “The situation is not going away,” says inspiring TB doctor

Interview: “The situation is not going away,” says inspiring TB doctor

Dr Juli Switala (42) has treated children in Nigeria, helped fatally ill patients during the 2014 Ebola outbreak in Sierra Leone, and delivered babies at a hospital in Afghanistan against a backdrop of upheaval and violence. But nowhere cuts close to her heart quite like Brooklyn Chest – the tuberculosis (TB) hospital on Cape Town’s north-western fringes. Biénne Huisman chatted with Switala about her work in hospitals around the world, the challenges of treating kids with TB, and going for a run to get away from it all.

Read More

In-depth: Can CO2 monitors help protect healthcare workers from TB?

In-depth: Can CO2 monitors help protect healthcare workers from TB?

A recent study published in the journal Clinical Infectious Diseases found that there was an association between healthcare workers’ exposure to high levels of carbon dioxide (CO2) and their risk of being exposed to tuberculosis (TB). Elri Voigt unpacks the study’s findings and asks experts how CO2 monitors work, how well they predict the risk of TB exposure, and in which settings these monitors might be most useful.

Read More

1 2 3 10