Health in 2025: The year in fewer than 1 000 words

The year’s biggest health story by far has been the cuts to US aid for health and US support for health research. But it’s also been a year of important HIV prevention developments, NHI court cases, ongoing crises in some of our provincial health departments, and some first steps toward accountability for the corruption at Tembisa Hospital.

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#InsideTheBox with Dr Andy Gray | Where are we on the road to more coherent cannabis regulation?

There has been much confusion and misunderstandings about how cannabis and associated products are regulated in South Africa, with government’s own missteps adding to the uncertainty. In his last #InsideTheBox column for the year, Dr Andy Gray clearly sets out the current legal and regulatory situation and where we’re heading.

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New hope after shuttered Hillbrow transgender clinic finds new partner in state hospital

United States funding cuts shredded specialised services at a transgender clinic in the heart of Johannesburg. But a new collaborative initiative refuses to let this be the end of the journey for trans clients. Journalist Ufrieda Ho and photographer Thom Pierce meet some of the people at the forefront of the project.

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Salim Abdool Karim | Transforming adversity into opportunity for the AIDS response

As World AIDS Day 2025 swings by, CAPRISA Director Professor Salim Abdool Karim reflects on the frantic days following this year’s unprecedented cuts to health aid and research funding from the US, arguing that the deliberate disruptiveness was designed to be cruel. Nonetheless, he argues, our HIV response must now forge ahead on a path that is more affordable, sustainable and independent.

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TIMELINE | The journey of HIV through science, struggle, activism, and hope

From the first reported cases of HIV in 1981 to the latest breakthroughs in long-acting prevention, this Spotlight timeline traces key moments in the global and South African response to the virus. It highlights scientific milestones, political controversies, activism, and the human stories that shaped one of the most significant public health challenges of our time.

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#InTheSpotlight | Why government should provide more free HIV self-tests

It is estimated that around half a million people living with HIV in South Africa don’t know they are living with the virus. One way to help these people is by offering them the means to test themselves in the privacy of their own homes. As Catherine Tomlinson explains in this #InTheSpotlight special briefing, such self-screening tests are part of our HIV response on paper, but in reality, the tests are massively underutilised.

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“What’s the point of top tech sitting in labs?” UCT’s Yumna Albertus is on a mission to turn science into social impact

What started as a childhood fascination with science and sport has grown into a mission to “democratise” technology with innovative, affordable rehabilitation solutions for people with limited resources. Biénne Huisman sits down with the associate professor – who was once a volleyball captain and is now the head of a top research centre – and who is proving that low-cost solutions are possible.

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Integrating health services for mom and baby could reduce clinic visits by half

In South Africa, many mothers and their babies have to visit the clinic more than 10 times in the first six months of the postnatal period. Early findings from an ongoing implementation science project suggests we can get this down to five. The hope is that the new approach will also help reduce HIV transmission from mothers to their babies. Elri Voigt reports.

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