Angst as South Africa’s HIV & TB Healthcare Worker Hotline goes offline

Angst as South Africa’s HIV & TB Healthcare Worker Hotline goes offline

A crucial hotline run for nearly 20 years from the slopes of Devil’s Peak in Cape Town for healthcare workers anywhere in South Africa, from the country’s busiest urban hospitals to far flung resource strained rural clinics, has been suspended due to a lack of funding.

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In The Spotlight | A fungal infection that targets the brain claims many lives in SA, stopping it won’t be easy

In The Spotlight | A fungal infection that targets the brain claims many lives in SA, stopping it won’t be easy

One of the top killers of people living with HIV in South Africa is a fungal infection caused by spores found all around us. In this Spotlight special briefing, Elri Voigt unpacks what we know about this dangerous disease called cryptococcal meningitis, why it remains so deadly, and what we can do about it.

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“This one was brought by God himself” – the doctor helping people see again in rural KZN

“This one was brought by God himself” – the doctor helping people see again in rural KZN

As a young doctor working in rural KwaZulu-Natal, Hennie Hamilton lived with a Zulu family for four years, an experience which, he says, changed him forever. Twenty-three years later, he’s still working in the area as medical manager at Mosvold Hospital and doing cataract surgery on patients from five rural hospitals.

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This specialist forensic nurse in Germiston helped put a serial rapist behind bars

This specialist forensic nurse in Germiston helped put a serial rapist behind bars

In a country like South Africa which grapples with a high prevalence of gender-based violence, forensic nursing unfortunately remains a largely overlooked specialisation, with little incentive for remuneration. One nurse tells Elna Schütz every flicker of hope a patient carries home is a reminder of why she chose this path.

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With over 3 600 Western Cape users, lenacapavir is “cool”

With over 3 600 Western Cape users, lenacapavir is “cool”

From counselling about small nodules to overcoming people’s fears of needles, Biénne Huisman takes the pulse of a new HIV prevention injection’s rollout in the Western Cape.

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SA is one step closer to a new TB vaccine, but there is a lot of work ahead

SA is one step closer to a new TB vaccine, but there is a lot of work ahead

In March 2024, a pivotal clinical trial was launched to evaluate what might well become the first new tuberculosis vaccine on the market in more than a century. As anticipation mounts for the trial to deliver results, Russell Rensburg argues that we need to start preparing for a rollout of the jab, but that we should think of preparation more widely than just the technicalities of regulatory approval and drug supply.

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In The Spotlight | What are broadly neutralising antibodies and what do they mean for the fight against HIV?

In The Spotlight | What are broadly neutralising antibodies and what do they mean for the fight against HIV?

HIV is known for its ability to outsmart our immune system’s normal defences. A small number of people living with HIV are however able to generate more effective immune responses to HIV. In this special briefing, Catherine Tomlinson zooms in on broadly neutralising antibodies, the secret sauce in these immune responses.

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Positive interim findings on new once-weekly HIV treatment pill

Positive interim findings on new once-weekly HIV treatment pill

A new antiretroviral combination pill that is taken only once a week appears to work as well as daily pills at treating HIV. This is according to interim study findings to be presented next week at the AIDS 2026 conference in Rio de Janeiro, Brazil.

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When medicines are made outside the factory: Why pharmacovigilance matters more than ever

When medicines are made outside the factory: Why pharmacovigilance matters more than ever

A high-profile court case has thrust the legalities of compounding medicines in South Africa into the spotlight. Behind the immediate legal issues, hide a series of unresolved questions about how we should ensure that compounded medicines used in South Africa are safe, argue Professor Renier Coetzee and Lara van Niekerk.

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“At the clinic … you can feel them staring” – How specialised services are helping trans people in George

“At the clinic … you can feel them staring” – How specialised services are helping trans people in George

An NGO offers safe, private HIV services to Men who Have Sex with Men and transgender people in George. Sue Segar met with some of the people using these services, and found the NGO, TB HIV Care are already providing relief from the hostile reactions trans people sometimes experience in government clinics.

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From test tubes to treatment: Two TB researchers on getting the ancient disease themselves

From test tubes to treatment: Two TB researchers on getting the ancient disease themselves

Being a researcher who studies tuberculosis in the lab is one thing, having the TB bug in your lungs is quite another. Elri Voigt sat down with two of a relatively small number of people who have experienced both.

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