In 2023, tuberculosis was again the top infectious disease killer on the planet, having temporarily been overtaken by COVID-19. Even so, investment in TB research is far below what United Nations agencies estimate is needed. Catherine Tomlinson unpacks a new report on global TB research funding, zooming in on the situation in South Africa.
Highly effective treatments for HIV have existed since the mid-1990s. But while these treatments keep people healthy, we do not yet have a safe and scalable way to completely rid the body of the virus. In this Spotlight special briefing, Elri Voigt takes stock of where we are in the decades-long search for an HIV cure.
Some patients at KwaZulu-Natal hospitals are donating lung tissue for use in TB research. Sue Segar tracks what happens to these tissue samples and explores why these samples are so important to unlocking the mysteries of what the TB bacterium does inside the human body.
An estimated 56 000 people in South Africa and 1.25 million around the world died of TB in 2023, according to just-published figures from the WHO. This means that in 2023 TB overtook COVID-19 as the top infectious disease killer on the planet. Marcus Low unpacks the new numbers.
Pregnant women are typically excluded from clinical trials of new TB medicines. This has led to a lack of solid scientific evidence on how best to treat women who fall ill with TB while they are expecting. Tiyese Jeranji asked local TB experts about the problem and puts the spotlight on a recent study that broke the mould by opening its doors to pregnant women.
Hillbrow started out as Johannesburg’s first health hub in the late 1880s. It’s also been a suburb associated with pimps and prostitution, a middle finger to the Nationalist Party, and a key site of the HIV crisis. Today, it’s the forgotten flatlands of inner city decay … but in small pockets it stays true to its heritage of bringing healthcare to the city’s most overlooked.
In June, we heard what could be this year’s biggest HIV breakthrough: a twice-yearly injection can prevent HIV infection. Findings from a second large study of the jab has now confirmed that it works. Elri Voigt goes over the new findings and unpacks the licenses that are expected to facilitate the availability of generic versions of the jab in over a hundred countries, including South Africa.
A series of robberies at healthcare facilities in the Eastern Cape has disrupted services, with patients sometimes left waiting outside while clinics limit the number of people allowed in. This follows the provincial health department spending over R700 million on security contracts in the past financial year, reports Luvuyo Mehlwana.
Stopping antiretroviral treatment when you are living with HIV can result in increased HIV transmission, illness, hospitalisation, and eventually death. To combat such disengagement with HIV treatment, Professor Graeme Meintjes and colleagues argue we need smarter differentiated care and better education of healthcare workers, people living with HIV, and communities.
The increased professionalisation of nursing in South Africa in recent years marks a significant shift in the perception and practice of this essential healthcare field. As the country grapples with a critical shortage of nurses and the ongoing challenges of aligning nursing education with new higher education standards, Thabo Molelekwa asks local experts about the future of nursing in the country.
South Africa has the third highest suicide rate in Africa and Africa has higher rates of suicide than any other continent. In the wake of World Suicide Prevention Day on September 10th, clinical psychologist Vincenzo Sinisi asks what can be done to bring down suicide rates.
COVID-19 temporarily reversed South Africa’s hard-won reduction in maternal mortality, but the death rate has now stabilised, and hopes are high that the downward trend will resume. However, if experts are right, we’re missing some crucial interventions that would further prevent what are avoidable deaths. Chris Bateman talks to some of the leading lights in the field.
