EDITORIAL | After major research cuts, SA charts a new path

EDITORIAL | After major research cuts, SA charts a new path

It has been a bruising year or so for medical researchers in South Africa with the US pausing, cancelling, and then resuming some grants. But as bad as things were, what played out wasn’t the worst case scenario, and momentum is now building toward recovery.

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SAMRC rolls out rescue grants: What next for research projects hit by US funding cuts?

SAMRC rolls out rescue grants: What next for research projects hit by US funding cuts?

Cuts in United States funding for global health research over the past year dealt a heavy blow to South Africa’s health research ecosystem, which has historically been heavily reliant on US financial support. Catherine Tomlinson looks at what the South African Medical Research Council has done to weather the storm and what they have planned for the next few years.

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“When other kids were playing with dolls, I was playing being a doctor”, says SA’s new HIV and TB Czar

“When other kids were playing with dolls, I was playing being a doctor”, says SA’s new HIV and TB Czar

Biénne Huisman meets South Africa’s recently appointed Deputy Director-General for HIV, AIDS, TB and sexually transmitted infections, discussing the latest HIV prevention medicines, her career turning points, and bedtime reading.

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What breakthrough weight loss meds might mean for people with HIV

What breakthrough weight loss meds might mean for people with HIV

In part 3 of a Spotlight special series on the role of new weight loss medicines like Ozempic in South Africa, we ask what these breakthrough jabs might mean for people living with HIV in the country. There is some tantalising early research on potential benefits, but also many uncertainties. Catherine Tomlinson reports.

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Global health infrastructure is changing. Why getting it right matters for SA

Global health infrastructure is changing. Why getting it right matters for SA

Funding cuts over the last year or so have created a crisis for multilateral health institutions. Which institutions emerge from this crisis, and in what form, will have real consequences for the health of people in South Africa, argues Spotlight editor Marcus Low.

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Early treatment helps protect the brains of people living with HIV

Early treatment helps protect the brains of people living with HIV

Antiretroviral therapy has shifted HIV from a fatal to a chronic condition. But neuropsychiatrists say it is imperative for people living with the virus to start treatment immediately as the “duration of untreated exposure” may cause irreversible brain damage and impact long-term cognitive health. Biénne Huisman reports.

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Behind the scenes: The amazing people driving a ‘truly South African’ HIV vaccine study

Behind the scenes: The amazing people driving a ‘truly South African’ HIV vaccine study

A cutting-edge, South African-led HIV vaccine trial built on decades of research recently kicked off in Cape Town. Elri Voigt unpacks what exactly is being studied, and how the resilience, tenacity and urgency of a group of dedicated South African researchers made it possible.

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Spotlight’s top 9 health stories to watch in 2026

Spotlight’s top 9 health stories to watch in 2026

From the limited rollout of a new HIV prevention jab to developments with new weight loss medicines, to high-stakes court cases relating to National Health Insurance (NHI), 2026 is set to be another tumultuous year in healthcare. Here are nine stories that Spotlight will keep a close eye on.

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Health in 2025: The year in fewer than 1 000 words

Health in 2025: The year in fewer than 1 000 words

The year’s biggest health story by far has been the cuts to US aid for health and US support for health research. But it’s also been a year of important HIV prevention developments, NHI court cases, ongoing crises in some of our provincial health departments, and some first steps toward accountability for the corruption at Tembisa Hospital.

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New hope after shuttered Hillbrow transgender clinic finds new partner in state hospital

New hope after shuttered Hillbrow transgender clinic finds new partner in state hospital

United States funding cuts shredded specialised services at a transgender clinic in the heart of Johannesburg. But a new collaborative initiative refuses to let this be the end of the journey for trans clients. Journalist Ufrieda Ho and photographer Thom Pierce meet some of the people at the forefront of the project.

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Salim Abdool Karim | Transforming adversity into opportunity for the AIDS response

Salim Abdool Karim | Transforming adversity into opportunity for the AIDS response

As World AIDS Day 2025 swings by, CAPRISA Director Professor Salim Abdool Karim reflects on the frantic days following this year’s unprecedented cuts to health aid and research funding from the US, arguing that the deliberate disruptiveness was designed to be cruel. Nonetheless, he argues, our HIV response must now forge ahead on a path that is more affordable, sustainable and independent.

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