Did US aid cuts break precisely the things we need most for the lenacapavir rollout?

With a new six-monthly injection, South Africa last week launched the most promising new HIV prevention tool in years, but much of the infrastructure that made HIV prevention services accessible to high-risk groups has been dismantled over the last year. Amy Green asks whether we can successfully deliver this breakthrough technology without the trusted pathways that were decimated by cuts to aid from the United States.

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Salim Abdool Karim | Transforming adversity into opportunity for the AIDS response

As World AIDS Day 2025 swings by, CAPRISA Director Professor Salim Abdool Karim reflects on the frantic days following this year’s unprecedented cuts to health aid and research funding from the US, arguing that the deliberate disruptiveness was designed to be cruel. Nonetheless, he argues, our HIV response must now forge ahead on a path that is more affordable, sustainable and independent.

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Francois Venter | Our HIV response will collapse without US funding – unless we act urgently

South Africa faces its worst health crisis in 20 years. Worse than COVID, and one that will overshadow diabetes as a major killer, while pouring petrol on a dwindling TB fire. But it is preventable, argues Professor Francois Venter if our government steps up urgently.

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US funding remains frozen for many life-saving services

Despite a waiver on life-saving humanitarian aid, USAID funding for crucial medical services remains frozen. Services remain closed as organisations await approval of revised budgets limited to what is allowed under the waiver. A separate US agency – the Centers for Disease Control and Prevention – restored funding to its beneficiary organisations, allowing them to reopen thanks to a US court judgment.

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Pretoria company aims to lead SA in making key TB drug ingredients

Though several South African companies are producing HIV and TB medicines, the active ingredients that go into these medicines are usually imported from India or China. Now, a local company is planning to break new ground by making the active ingredients for two important TB medicines in Pretoria. Catherine Tomlinson zooms in on the company’s efforts and outlines some of the obstacles to getting such local production off the ground.

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