XACT III: A trial asking how to take TB tests to the people

XACT III: A trial asking how to take TB tests to the people

Roughly two in five people newly ill with TB worldwide are never diagnosed. In South Africa, this amounts to about 120 000 to 160 000 people per year. A large new study called XACT III is testing ways in which more people can be diagnosed and started on TB treatment more quickly. Tiyese Jeranji reports.

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For next pandemic we need vaccines in 100 days, says expert

For next pandemic we need vaccines in 100 days, says expert

Developing COVID-19 vaccines in less than a year came from repurposing multiple, decade-old vaccine research platforms, but too many lives were lost, and a new goal of developing vaccines in 100 days is needed to counter the next global pathogen, experts say.

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Opinion: Treat us better if you want us to keep coming back

Opinion: Treat us better if you want us to keep coming back

People who miss appointments or stop taking their treatment often report being treated badly by healthcare workers when they return to health facilities. This fear of being reprimanded discourages people from going back to the clinic to seek support and receive their treatment, argues Bellinda Setshogelo and Sibongile Tshabalala.

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After setbacks, rollout of new TB prevention pills to start in six districts

After setbacks, rollout of new TB prevention pills to start in six districts

After various delays and setbacks, a new, less toxic, short-course tuberculosis preventive therapy called 3HP is finally being launched in six districts in South Africa. Tiyese Jeranji reports.

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HIV and cervical cancer: Behind SA’s extraordinarily high numbers

HIV and cervical cancer: Behind SA’s extraordinarily high numbers

A study recently published in The Lancet found that women living with HIV made up an astonishing 63.4% of new cervical cancer cases in South Africa in 2018. Elri Voigt spoke to local experts about the links between HIV and cervical cancer in South Africa and how cervical cancer is prevented, tested for, and treated in the public sector.

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Opinion: Longer HIV treatment supplies can support better long term adherence

Opinion: Longer HIV treatment supplies can support better long term adherence

One of the biggest challenges now facing South Africa’s HIV response is how to support many more people living with HIV to engage or re-engage and then stay on treatment. One way to make it easier for people living with HIV to adhere to treatment is to provide a longer supply of medicines, argues Ndivhuwo Rambau & Simphiwe Xaba.

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In-depth: Promising signs for local biopharmaceutical production

In-depth: Promising signs for local biopharmaceutical production

Biopharmaceuticals are therapeutic drugs, vaccines, and diagnostics in which the active ingredient is produced in a living substance such as eggs or tobacco plants. The living substance acts as a ‘miniature factory’ in which the active ingredient is grown and replicated. Catherine Tomlinson takes a deep dive into the fascinating research and other initiatives in South Africa aimed at spurring local production of these products – and asks why a Cape Town-based company opted to set up a manufacturing plant in Mauritius rather than at home.

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New TB testing strategy ups diagnosis in clinics by 17%

New TB testing strategy ups diagnosis in clinics by 17%

Around 360 000 to 390 000 people in South Africa fall ill with tuberculosis (TB) every year. Of these, around 120 000 to 150 000 are never diagnosed. Now a new TB testing strategy has been shown to improve TB detection at clinics by 17%. Tiyese Jeranji reports.

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In-depth: What we know about SA’s rampant gonorrhoea epidemic

In-depth: What we know about SA’s rampant gonorrhoea epidemic

Despite the global emergence of highly resistant strains of gonorrhoea, including untreatable variants, a new antibiotic for the disease has not been developed in over half a century. In January, a trial began in South Africa and other countries for a new gonorrhoea antibiotic. But what is gonorrhoea? How significant is the problem in South Africa and among those living with HIV? Do we have resistant strains too? Experts report a grim situation, but with hope on the horizon. Amy Green reports.

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New men’s health centre in Cape metro welcomed

New men’s health centre in Cape metro welcomed

The Western Cape Department of Health recently opened a new men’s only health centre, which aims to empower boys and men to lead healthy lives. Siyabonga Kamnqa spoke to the centre’s manager and men’s health organisations about the value this centre will add and the services it provides.

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Why broadly neutralising antibodies might be the next big thing in HIV

Why broadly neutralising antibodies might be the next big thing in HIV

We know antiretroviral therapy can prevent HIV infection, but can natural biological substances do the same? The results of a recent scientific trial have answered this question: Yes, using broadly neutralising antibodies. But what are broadly neutralising antibodies? How do they work? And when will the average person get access to them? Amy Green breaks down the science.

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Tens of thousands of people with TB in SA not diagnosed, survey

Tens of thousands of people with TB in SA not diagnosed, survey

Over 150 000 people who had TB in South Africa in 2018 were not diagnosed, according to findings from South Africa’s long-awaited National Tuberculosis Prevalence Survey. One reason for this is that an unexpectedly high number of people do not show the typical TB symptoms and are never x-rayed. Amy Green reports.

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