A Supreme Court of Appeal ruling in October 2025 cleared the way for specially trained and permitted pharmacists to dispense antiretroviral medicines without a doctor’s script. Seven months later, no pharmacists are yet providing these services. Catherine Tomlinson explores the reasons for the delay.
HIV treatment has been improved and simplified significantly over the years yet a small fraction of people living with HIV still take complex multi-pill regimens. Elri Voigt reports on a new combination pill that could make life easier for some in this group. But as two leading experts point out, the development comes against a backdrop where the traditional categorisation of HIV medicines is dissolving.
By March 2027, the health department aims to have 1.5 million people living with HIV on a new programme where they can get a six-month supply of antiretroviral medicines at a time. Early indications suggest that implementation of the programme is slow and uneven, reports Christina Pitt.
The number of people in South Africa on antiretroviral treatment remained roughly unchanged from 2024 to 2025, according to just-published estimates from the leading mathematical model of HIV in the country. This suggests that the disruption of US aid for HIV services has slowed the growth of our HIV treatment programme, but the impact so far is not as severe as some researchers feared it might be. Marcus Low reports.
Along dusty roads in northern KwaZulu-Natal, Biénne Huisman speaks to youth leaders, community mentors and leading scientists who are collaborating to bring a groundbreaking HIV prevention jab to this area where HIV infection rates remain stubbornly high.
At his Durban office, Professor Willem Hanekom tells Biénne Huisman about taking a ventilated young patient to the Sea Point promenade, living with HIV, the need for an African research agenda, and the recurring joy that has defined his career.
It has been a bruising year or so for medical researchers in South Africa with the US pausing, cancelling, and then resuming some grants. But as bad as things were, what played out wasn’t the worst case scenario, and momentum is now building toward recovery.
Cuts in United States funding for global health research over the past year dealt a heavy blow to South Africa’s health research ecosystem, which has historically been heavily reliant on US financial support. Catherine Tomlinson looks at what the South African Medical Research Council has done to weather the storm and what they have planned for the next few years.
Biénne Huisman meets South Africa’s recently appointed Deputy Director-General for HIV, AIDS, TB and sexually transmitted infections, discussing the latest HIV prevention medicines, her career turning points, and bedtime reading.
In part 3 of a Spotlight special series on the role of new weight loss medicines like Ozempic in South Africa, we ask what these breakthrough jabs might mean for people living with HIV in the country. There is some tantalising early research on potential benefits, but also many uncertainties. Catherine Tomlinson reports.
Funding cuts over the last year or so have created a crisis for multilateral health institutions. Which institutions emerge from this crisis, and in what form, will have real consequences for the health of people in South Africa, argues Spotlight editor Marcus Low.
Antiretroviral therapy has shifted HIV from a fatal to a chronic condition. But neuropsychiatrists say it is imperative for people living with the virus to start treatment immediately as the “duration of untreated exposure” may cause irreversible brain damage and impact long-term cognitive health. Biénne Huisman reports.