COVID-19: The role of next-generation vaccines in immunity

Indications are that the virus that causes COVID-19 is going to continue evolving and escaping the protection against infection people already have. Researchers are working on next-generation vaccines tailored to fight off specific versions of the virus, like the Omicron sub-lineages BA.4 and BA.5. But can these new vaccines be tested and produced fast enough to keep up with the rapidly changing virus? Aisha Abdool Karim asked some local experts.

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COVID-19: What tests are available in SA and which ones to use?

The different types of COVID-19 tests are far from equal. Picking a test is generally a matter of speed versus accuracy and, most importantly, why you need a test and when. What are the limitations of these tests? Is there any quality control? What are the chances of false positives and false negatives? Elsabé Brits surveys the landscape of tests available in South Africa and asks which type is most appropriate in what situation.

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Where are we in the race for a HIV vaccine?

While progress in the race for effective COVID-19 vaccines has been rapid and impressive, an effective HIV vaccine remains elusive. As part of Spotlight’s World AIDS Day 2020 coverage, Kathryn Cleary asks two of South Africa’s top vaccine researchers to update us on where we are in the race for an HIV vaccine.

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