From the ongoing political and legal battles over NHI, to the far-reaching health impacts of political change in the United States, it is set to be another tumultuous year for healthcare in South Africa and around the globe. Here’s Spotlight’s top four healthcare questions for 2025.
In 2023, tuberculosis was again the top infectious disease killer on the planet, having temporarily been overtaken by COVID-19. Even so, investment in TB research is far below what United Nations agencies estimate is needed. Catherine Tomlinson unpacks a new report on global TB research funding, zooming in on the situation in South Africa.
From the NHI Act to major advances in HIV prevention, it has been another busy year in the world of healthcare. Spotlight editors Marcus Low and Adiel Ismail recap the year’s health developments and identify some key trends in fewer than 1 000 words.
Though several South African companies are producing HIV and TB medicines, the active ingredients that go into these medicines are usually imported from India or China. Now, a local company is planning to break new ground by making the active ingredients for two important TB medicines in Pretoria. Catherine Tomlinson zooms in on the company’s efforts and outlines some of the obstacles to getting such local production off the ground.
There is a history of competition law being used to drive HIV medicine prices lower in South Africa. Now, two cases involving cancer medicines seem set to nail down what qualifies as “excessive pricing” in South African law – a legal development that could have far reaching implications for medicines prices in the country. Catherine Tomlinson unpacks the details.
Over the last decade, it has become clear that South Africa’s progress against TB depends on diagnosing more people more quickly. In this Spotlight special briefing, Marcus Low asks how we can best go about it.
Some patients at KwaZulu-Natal hospitals are donating lung tissue for use in TB research. Sue Segar tracks what happens to these tissue samples and explores why these samples are so important to unlocking the mysteries of what the TB bacterium does inside the human body.
An estimated 56 000 people in South Africa and 1.25 million around the world died of TB in 2023, according to just-published figures from the WHO. This means that in 2023 TB overtook COVID-19 as the top infectious disease killer on the planet. Marcus Low unpacks the new numbers.
Pregnant women are typically excluded from clinical trials of new TB medicines. This has led to a lack of solid scientific evidence on how best to treat women who fall ill with TB while they are expecting. Tiyese Jeranji asked local TB experts about the problem and puts the spotlight on a recent study that broke the mould by opening its doors to pregnant women.
Hillbrow started out as Johannesburg’s first health hub in the late 1880s. It’s also been a suburb associated with pimps and prostitution, a middle finger to the Nationalist Party, and a key site of the HIV crisis. Today, it’s the forgotten flatlands of inner city decay … but in small pockets it stays true to its heritage of bringing healthcare to the city’s most overlooked.
With varying degrees of success, artificial intelligence has begun to play the role of research assistant, radiologist, health educator, and even therapist. In this Spotlight special briefing, Jesse Copelyn tries to see past the hype and pin-points the most immediate implications of these new technologies for healthcare in South Africa.
A Competition Commission probe recently resulted in a patent on an important tuberculosis medicine being dropped in South Africa. Twenty years ago, a similar Competition Commission case resulted in a settlement that helped drive down the prices of several antiretrovirals, thereby helping to set the stage for the country’s HIV treatment programme. Fatima Hassan and Leena Menghaney connect the dots between the two landmark cases and map out what has and has not changed over the last two decades.
