A high-profile court case has thrust the legalities of compounding medicines in South Africa into the spotlight. Behind the immediate legal issues, hide a series of unresolved questions about how we should ensure that compounded medicines used in South Africa are safe, argue Professor Renier Coetzee and Lara van Niekerk.
Eight months after the Supreme Court of Appeal gave the green light for specially trained pharmacists to dispense antiretrovirals without a script from a doctor, the programme remains stuck in the starting blocks. With enabling permits now seemingly on the horizon, Angela Tembo and Dr Deanne Johnston ask if there has been sufficient planning to make the initiative a success.
The South African Health Products Regulatory Authority, with the South African Pharmacy Council, recently announced what was described as a crackdown on a compounding pharmacy. They allege “critical regulatory non-compliance” in relation to the compounding of unregistered medicines. In his latest Inside The Box column, Dr Andy Gray provides some background to the issues at stake, while recognising that some key elements remain contested.
A Supreme Court of Appeal ruling in October 2025 cleared the way for specially trained and permitted pharmacists to dispense antiretroviral medicines without a doctor’s script. Seven months later, no pharmacists are yet providing these services. Catherine Tomlinson explores the reasons for the delay.
Medicines are among the most powerful tools in healthcare, but they also come with risks. As we mark #MedSafetyWeek, Mr Vincent Tlala, registrar and CEO of the South African Pharmacy Council, argues that the safe use of medicines is a shared responsibility, and is not only up to pharmacists.
A landmark ruling from the Supreme Court of Appeal means specially trained pharmacists will soon be allowed to dispense antiretrovirals without a doctor’s script. Pharmacists with the required training will need special permits from the director general of health. While no pharmacists yet hold these permits, Catherine Tomlinson reports that they may be able to start applying for them as soon as next month.
