The evolution of HIV treatment: From multi-pill regimens to better, single pill combos

HIV treatment has been improved and simplified significantly over the years yet a small fraction of people living with HIV still take complex multi-pill regimens. Elri Voigt reports on a new combination pill that could make life easier for some in this group. But as two leading experts point out, the development comes against a backdrop where the traditional categorisation of HIV medicines is dissolving.

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TIMELINE | The journey of HIV through science, struggle, activism, and hope

From the first reported cases of HIV in 1981 to the latest breakthroughs in long-acting prevention, this Spotlight timeline traces key moments in the global and South African response to the virus. It highlights scientific milestones, political controversies, activism, and the human stories that shaped one of the most significant public health challenges of our time.

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ARVs without a script: What next after major court ruling?

A landmark ruling from the Supreme Court of Appeal means specially trained pharmacists will soon be allowed to dispense antiretrovirals without a doctor’s script. Pharmacists with the required training will need special permits from the director general of health. While no pharmacists yet hold these permits, Catherine Tomlinson reports that they may be able to start applying for them as soon as next month.

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US pulls funding for South African medical research

US funding for clinical research in South Africa is incrementally being cancelled. This is happening through at least two processes – the first is by banning certain kinds of foreign grants called sub-awards (which is affecting everyone globally). The second is by failing to issue routine renewals of grants for clinical studies in South Africa. Spotlight and GroundUp break down the current situation.

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