In-depth: Can CO2 monitors help protect healthcare workers from TB?

A recent study published in the journal Clinical Infectious Diseases found that there was an association between healthcare workers’ exposure to high levels of carbon dioxide (CO2) and their risk of being exposed to tuberculosis (TB). Elri Voigt unpacks the study’s findings and asks experts how CO2 monitors work, how well they predict the risk of TB exposure, and in which settings these monitors might be most useful.

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Digital X-rays boosting TB diagnosis, assessment finds

Many people with tuberculosis (TB) in South Africa are never diagnosed or are diagnosed only once their symptoms have become quite severe. One solution to diagnosing more people more quickly is the expanded use of new digital X-ray technology. Now, an independent assessment of digital X-ray pilot projects in six districts in South Africa sheds light on how well this intervention works in the real world. Tiyese Jeranji reports.

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Positive signs for new TB testing strategy

Under a new tuberculosis (TB) diagnosis strategy, people considered to be at high risk of TB are offered molecular TB tests, even if they do not have any symptoms. A landmark study in 2020 showed that such a strategy can help diagnose more people more quickly. Now, early indications are that it also works in the real world and South Africa’s lab service says they can cope with the increased demand. Tiyese Jeranji reports.

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In-depth: Landmark moment as AI beats humans in reading X-rays for TB

“The results are in: artificial intelligence (AI) outperforms humans at reading chest X-rays for signs of tuberculosis,” proclaimed a recent newsletter of the Stop TB Partnership. Tiyese Jeranji spoke to a variety of experts about the landmark study behind this proclamation and asked what AI-aided X-ray interpretation may mean for countries like South Africa with high TB burdens.

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TB in children: Exciting treatment advances, but better tests badly needed

Children shoulder approximately 12% of the global TB burden, and this proportion is likely higher in high TB burden countries. In South Africa, up to 30 000 children develop TB each year. Tiyese Jeranji spoke to TB expert, Dr Megan Palmer from Brooklyn Chest Hospital about treatment challenges and how to improve TB detection and treatment outcomes in children.

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