Important TB drug as effective at lower dose, study finds

Important TB drug as effective at lower dose, study finds

The treatment of drug-resistant forms of tuberculosis has been transformed over the last decade with treatment becoming more effective, safer, and treatment duration in many cases dropping to under a year. Even so, treatment can still come with serious side effects and for some, it can still last over a year and a half. In a finding that may help further reduce side effects, new research has found that the dosage of a key drug can be lowered without compromising how well it works. Tiyese Jeranji and Marcus Low report.

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Western Cape to launch COVID-style tuberculosis dashboard

Western Cape to launch COVID-style tuberculosis dashboard

The COVID-19 pandemic caused huge setbacks for the fight against TB. Now, provinces are developing TB catch-up plans. The Western Cape Department of Health will soon launch a TB dashboard as part of its “multi-sectorial TB emergency response plan”. Tiyese Jeranji reports.

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SA piloting mobile X-rays to improve TB detection

SA piloting mobile X-rays to improve TB detection

South Africa’s first National Tuberculosis Prevalence Survey found that many people without TB symptoms nevertheless have TB disease that can be detected using chest X-rays. Accordingly, new mobile X-ray screening programmes are being piloted in a number of provinces. Tiyese Jeranji reports.

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400 people in SA with highly drug-resistant TB to get new three-drug regimen

400 people in SA with highly drug-resistant TB to get new three-drug regimen

Treating highly drug-resistant forms of tuberculosis can take anything from nine to 24 months and patients have to contend with various unpleasant, and sometimes dangerous, side effects. A new six-month regimen made up of just three drugs that will be offered to 400 patients in South Africa might offer a better solution for some. Tiyese Jeranji reports.

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X-rays and AI could transform TB detection in SA, but red tape might delay things

X-rays and AI could transform TB detection in SA, but red tape might delay things

New World Health Organization guidance released this week endorses the wider use of chest X-rays and artificial intelligence for tuberculosis detection. Before these technologies can be fully utilised in South Africa, some regulatory and other issues will first have to be sorted out. Catherine Tomlinson reports.

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Reimagining health in the Eastern Cape: As budgets shrink, it is more important than ever to strengthen primary healthcare

Reimagining health in the Eastern Cape: As budgets shrink, it is more important than ever to strengthen primary healthcare

As the final negotiations in the 2021 budget process unfold, the government of the Eastern Cape and the department of health in particular are being asked to do more with less. It is now more urgent than ever to strengthen public primary health care, argue Ektaa Deochand and Russell Rensburg.

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In-depth: Getting Gauteng’s HIV and TB response back on track

In-depth: Getting Gauteng’s HIV and TB response back on track

From March to July this year, the Gauteng Department of Health recorded 57 848 TB tests – a decrease of about 30 000 tests compared to the same period last year. The province performed better with HIV testing, although the HIV response has faltered in other areas. Melissa Javan makes sense of the province’s numbers and speaks to activists and community health workers about the impact of lockdown on their services and plans to get things back on track.  

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TB in children: Exciting treatment advances, but better tests badly needed

TB in children: Exciting treatment advances, but better tests badly needed

Children shoulder approximately 12% of the global TB burden, and this proportion is likely higher in high TB burden countries. In South Africa, up to 30 000 children develop TB each year. Tiyese Jeranji spoke to TB expert, Dr Megan Palmer from Brooklyn Chest Hospital about treatment challenges and how to improve TB detection and treatment outcomes in children.

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Eastern Cape government mum on TB plans and numbers

Eastern Cape government mum on TB plans and numbers

Numbers from the National Institute of Communicable Disease and from some provinces show that TB diagnoses have dropped dramatically in 2020 – likely due to COVID-19 and the related lockdown. The Eastern Cape Department of Health has however declined to share information on the TB situation in the province and their catch-up plans. Some activists are concerned about the situation. Luvuyo Mehlwana reports.

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TB treatment time cut by a third

TB treatment time cut by a third

A new four-month treatment course for drug-sensitive tuberculosis (the most common form of TB by far) is as safe and effective as the current six-month treatment course that has been in use since the 1980s, according to findings from a large new study. Amy Green reports.

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Opinion: Release of SA’s first National TB Prevalence Survey should not be delayed any longer

Opinion: Release of SA’s first National TB Prevalence Survey should not be delayed any longer

Even though it has been ready for months, findings of a critically important tuberculosis survey have not been made public. Every day that passes, the more outdated the findings become, and accordingly the less useful.

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Drop in DR-TB detection points to “crisis” in SA’s TB response

Drop in DR-TB detection points to “crisis” in SA’s TB response

A leading TB doctor says that “it is no exaggeration to say there is a TB crisis in the country”, and that “the impact of this crisis could be even more devastating than COVID-19”. Kathryn Cleary explores the COVID-19 pandemic’s impact on South Africa’s TB response and the way forward.

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