Some patients at KwaZulu-Natal hospitals are donating lung tissue for use in TB research. Sue Segar tracks what happens to these tissue samples and explores why these samples are so important to unlocking the mysteries of what the TB bacterium does inside the human body.
An estimated 56 000 people in South Africa and 1.25 million around the world died of TB in 2023, according to just-published figures from the WHO. This means that in 2023 TB overtook COVID-19 as the top infectious disease killer on the planet. Marcus Low unpacks the new numbers.
Pregnant women are typically excluded from clinical trials of new TB medicines. This has led to a lack of solid scientific evidence on how best to treat women who fall ill with TB while they are expecting. Tiyese Jeranji asked local TB experts about the problem and puts the spotlight on a recent study that broke the mould by opening its doors to pregnant women.
Most tuberculosis (TB) tests still require a trip to the clinic. Now, new technology has made it possible to test people at home. This could be a big deal for South Africa, where much TB goes undiagnosed. Tiyese Jeranji unpacks the findings and implications of a recent study into such TB home testing.
Besides preventing illness and death, tuberculosis prevention therapy is estimated to be highly cost effective. Yet, uptake of the medication is not what it could be in South Africa. Tiyese Jeranji asks how much has changed since the Department of Health last year decided to make TB prevention therapy much more widely available.
At the age of 19 Phumeza Tisile contracted multidrug-resistant tuberculosis. For four years she battled the disease, losing her hearing in the process. At one stage, a doctor told her to visit a priest and prepare her soul for death. Recently, Tisile (now 33) made it on to TIME magazine’s 2023 TIME100 Next list, as one of 100 emerging leaders round the world who are “shaping the future and defining the next generation of leadership”. Sue Segar chatted to Tisile about her remarkable journey.
People in South Africa who fall ill with tuberculosis (TB) often also have other health issues. HIV, which drives much of the TB epidemic in South Africa, is the most obvious co-infection, but people who fall ill with TB are also more likely to have diabetes and mental health problems than the general public. Tiyese Jeranji spoke to local experts about the interesting links between TB and liver problems.
South Africa’s National Strategic Plan for HIV, TB and STIs (2023 – 2028) was launched on Friday at Tlhabane Stadium in Rustenburg, North West as the world commemorated World TB Day. Nthusang Lefafa attended the event and spoke to experts and activists about the state of TB and HIV and the work that lies ahead with the new NSP.
The South African TB Recovery Plan was developed to try and reverse the negative effects of the COVID-19 pandemic on the country’s TB response. On World TB Day, authors from TB Proof (a leading TB activist group) assess how the recovery is going and identify four key areas where further intervention is needed.
Tuberculosis (TB) disease and all the disruption and stress that goes along with it can take a toll on someone’s mental health, and mental health problems can in turn make someone more vulnerable to TB. In the wake of World Mental Health Day 2022, Tiyese Jeranji explores the complex links between mental health and TB.
South Africa last published comprehensive guidelines for the management of childhood tuberculosis (TB) in 2013. Almost a decade later, the guidelines are being updated to recommend a shortened TB treatment regimen for most children with pulmonary TB. Catherine Tomlinson reports.
A new six-month treatment regimen for drug-resistant forms of tuberculosis is expected to be rolled out in the public sector later this year – current regimens take anything from nine to 18 months. Catherine Tomlinson unpacks why the switch is important and outlines what still needs to happen to make it a reality.
