In-depth: How big a problem is TB in SA’s schools?

While there is limited data on tuberculosis (TB) in South Africa’s schools, a growing body of evidence suggests that there is indeed significant TB transmission taking place in the country’s often over-crowded classrooms. Tiyese Jeranji spoke to several local experts about what we do and do not know about the impact this age-old disease is having on our learners and their households.

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Funding secured for massive TB vaccine trial

A massive and much-anticipated phase 3 trial of an experimental tuberculosis (TB) vaccine is set to proceed after funding for it has been secured from two large philanthropies. If the trial’s findings are positive, the vaccine is likely to become the first new TB vaccine in over a hundred years to be widely used. Marcus Low reports.

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Opinion: Making good on the promise of SA’s TB Recovery Plan

The South African TB Recovery Plan was developed to try and reverse the negative effects of the COVID-19 pandemic on the country’s TB response. On World TB Day, authors from TB Proof (a leading TB activist group) assess how the recovery is going and identify four key areas where further intervention is needed.

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Supply issues delaying wider rollout of shorter TB preventive therapy

South Africa’s recently published guidelines for the treatment of tuberculosis (TB) infection have been welcomed by several experts. Among others, the guidelines endorse the use of a three-month course of TB preventive therapy as opposed to the old six-month course. But, while the intention is to roll out the three-month course quite widely, supply constraints may delay things. Tiyese Jeranji reports.

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Are oral swabs the future of TB testing?

The World Health Organization estimates that every year 40% of people who fall ill with TB globally are not diagnosed. There is thus an urgent need for faster, safe, and more convenient TB tests. The current gold standard for testing still requires people to cough up sputum, something that some people and children, in particular, struggle with. Tiyese Jeranji looks at the potential of a new experimental oral swab TB test.

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Opinion: Six ways clinics can help turn the tide on TB infection

Six simple interventions are at the heart of how clinics can be part of turning the tide on TB infection. By following a checklist of good practice, clinics can be safer for patients and staff. However, most clinics are failing to implement enough of these measures, putting people at risk of getting TB while waiting at the clinic, argues representatives from the community clinic monitoring group Ritshidze.

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In-depth: SA at cutting edge of TB vaccine research

It is a hundred years since the BCG vaccine, the only registered vaccine proven to offer some protection against tuberculosis (TB), was first used in people. Now researchers in South Africa are at the forefront of clinical trials testing experimental new TB vaccines. Adele Baleta reports.

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Tens of thousands of people with TB in SA not diagnosed, survey

Over 150 000 people who had TB in South Africa in 2018 were not diagnosed, according to findings from South Africa’s long-awaited National Tuberculosis Prevalence Survey. One reason for this is that an unexpectedly high number of people do not show the typical TB symptoms and are never x-rayed. Amy Green reports.

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