Important TB drug as effective at lower dose, study finds

Important TB drug as effective at lower dose, study finds

The treatment of drug-resistant forms of tuberculosis has been transformed over the last decade with treatment becoming more effective, safer, and treatment duration in many cases dropping to under a year. Even so, treatment can still come with serious side effects and for some, it can still last over a year and a half. In a finding that may help further reduce side effects, new research has found that the dosage of a key drug can be lowered without compromising how well it works. Tiyese Jeranji and Marcus Low report.

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Old struggles persist for CHWs in Free State

Old struggles persist for CHWs in Free State

Seven years after over 100 community health workers were arrested during a vigil at the provincial health department’s headquarters, Bophelo House, the struggles of community healthcare workers in the Free State continue as they are still calling for job security. Refilwe Mochoari reports.

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In Focus: Global strategy to end Cryptococcal Meningitis in people living with HIV

In Focus: Global strategy to end Cryptococcal Meningitis in people living with HIV

Cryptococcal meningitis is the second biggest killer of people living with HIV after tuberculosis (TB). Now, a global initiative, the Ending Cryptococcal Meningitis Deaths by 2030 Strategic Framework aims to get the gold standard drug to treat cryptococcal meningitis – flucytosine – registered in countries that need it. Amy Green reports.

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Like a “blanket of fatigue” – Inside Groote Schuur’s long-COVID clinic

Like a “blanket of fatigue” – Inside Groote Schuur’s long-COVID clinic

As a third wave of COVID-19 looms in the Western Cape, a group of doctors at Groote Schuur Hospital’s Post-COVID-19 Lung Disease Clinic are treating patients who have recovered from COVID-19 but who suffer lingering symptoms such as fatigue and shortness of breath. Bienne Huisman paid them a visit.

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Western Cape to launch COVID-style tuberculosis dashboard

Western Cape to launch COVID-style tuberculosis dashboard

The COVID-19 pandemic caused huge setbacks for the fight against TB. Now, provinces are developing TB catch-up plans. The Western Cape Department of Health will soon launch a TB dashboard as part of its “multi-sectorial TB emergency response plan”. Tiyese Jeranji reports.

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Analysis: We need to do for TB vaccines what we’ve done for COVID-19

Analysis: We need to do for TB vaccines what we’ve done for COVID-19

It is little wonder that some TB vaccine researchers suffer from a rare syndrome that understandably threatens their mental health. Symptoms include frustration, impatience, irritability, seemingly inexplicable rage, and in the least resilient, despair. It’s called VJS or vaccine jealousy syndrome, writes Chris Bateman.

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XACT III: A trial asking how to take TB tests to the people

XACT III: A trial asking how to take TB tests to the people

Roughly two in five people newly ill with TB worldwide are never diagnosed. In South Africa, this amounts to about 120 000 to 160 000 people per year. A large new study called XACT III is testing ways in which more people can be diagnosed and started on TB treatment more quickly. Tiyese Jeranji reports.

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For next pandemic we need vaccines in 100 days, says expert

For next pandemic we need vaccines in 100 days, says expert

Developing COVID-19 vaccines in less than a year came from repurposing multiple, decade-old vaccine research platforms, but too many lives were lost, and a new goal of developing vaccines in 100 days is needed to counter the next global pathogen, experts say.

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Opinion: Six ways clinics can help turn the tide on TB infection

Opinion: Six ways clinics can help turn the tide on TB infection

Six simple interventions are at the heart of how clinics can be part of turning the tide on TB infection. By following a checklist of good practice, clinics can be safer for patients and staff. However, most clinics are failing to implement enough of these measures, putting people at risk of getting TB while waiting at the clinic, argues representatives from the community clinic monitoring group Ritshidze.

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SA piloting mobile X-rays to improve TB detection

SA piloting mobile X-rays to improve TB detection

South Africa’s first National Tuberculosis Prevalence Survey found that many people without TB symptoms nevertheless have TB disease that can be detected using chest X-rays. Accordingly, new mobile X-ray screening programmes are being piloted in a number of provinces. Tiyese Jeranji reports.

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Support for some TB patients just a phone call away

Support for some TB patients just a phone call away

With just a tap of a finger, some people with drug-resistant tuberculosis can get in touch with a counsellor to get support over the phone. Tiyese Jeranji looks at a telephone support project that has helped keep some people with TB connected with their healthcare workers during the most difficult periods of the COVID-19 pandemic.

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Opinion: Health budget slashed despite vaccine commitments

Opinion: Health budget slashed despite vaccine commitments

The national budget tabled this week shows that planned spending on public health is reduced by a massive R50.3 billion over the next three years. We cannot accept a vaccine versus health system trade-off. Government must both expedite the procurement of vaccines and ensure that provinces have the staff and other capabilities to rapidly roll them out and to maintain and improve the quality of healthcare services, argue writers from SECTION27.

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