Falling ill with tuberculosis (TB) can be challenging for anyone, but it can be especially hard if you are pregnant or have just given birth. Globally, TB is amongst the top five causes of death in women of childbearing age. Tiyese Jeranji spoke to experts about the risks, challenges, and ongoing studies on maternal TB.
On December 12, Ntimbwe Munongo Mpamba will celebrate his fortieth birthday with chocolate cake in Northgate, Johannesburg. He was born with HIV but only became aware of his HIV status many years later. Biénne Huisman spoke to him about living with HIV, his early years when his mother fed him medicine disguised as sweets, and now, living openly as an HIV awareness champion.
Tuberculosis (TB) can be resistant to treatment with several different drugs. Tests that identify which drugs someone’s TB is resistant to are critical to ensuring that people are not treated with drugs that don’t work for them, especially given the significant side effects associated with some of the drugs. Elri Voigt assesses the state of play in testing for TB drug resistance and the promise of exciting new technologies, such as whole genome sequencing.
Some cases of tuberculosis (TB) can be successfully treated in as little as two months – a third of the current standard of six months. This is according to early findings from the landmark TRUNCATE TB trial presented at last week’s Union World Conference on Lung Health. Elri Voigt reports.
In 2021, an estimated 304 000 people in South Africa fell ill with tuberculosis and 56 000 died from the disease, according to new World Health Organization (WHO) figures released on Thursday. Elri Voigt unpacks the latest findings and asks local experts for their responses.
In 2015, the World Health Organization recommended a urine test that helps with the detection of tuberculosis (TB) in people living with HIV who are hospitalised or who have compromised immune systems. While uptake of this test in South Africa was initially quite slow, numbers presented at the recent South African TB Conference suggest that the use of the test is now increasing. Tiyese Jeranji reports.
When Novel Chegou first arrived in Stellenbosch from Cameroon in 2004 he sold African crafts at a stall next to the town’s village green to save money for his studies. Today, Professor Chegou is one of South Africa’s leading tuberculosis researchers. Biénne Huisman caught up with Chegou shortly after the announcement that he had been awarded the Royal Society Africa Prize.
South Africa last published comprehensive guidelines for the management of childhood tuberculosis (TB) in 2013. Almost a decade later, the guidelines are being updated to recommend a shortened TB treatment regimen for most children with pulmonary TB. Catherine Tomlinson reports.
South Africa’s tuberculosis (TB) testing numbers have recovered from dramatic declines in 2020, delegates heard at the opening of the 7th South African TB Conference in Durban. The Department of Health also provided some details of its TB recovery plans and targets. Tiyese Jeranji reports from Durban.
Tuberculosis can be challenging to diagnose in children, especially very young children. This is because it is difficult for them to cough up the sputum required by gold standard molecular tests and because they have fewer TB organisms in their sputum than adults. X-ray screening may be part of the solution, but it has shortcomings. Following some interesting recent study findings, Tiyese Jeranji asks what role lung ultrasound may have in improving TB detection in kids.
The World Health Organization estimates that every year 40% of people who fall ill with TB globally are not diagnosed. There is thus an urgent need for faster, safe, and more convenient TB tests. The current gold standard for testing still requires people to cough up sputum, something that some people and children, in particular, struggle with. Tiyese Jeranji looks at the potential of a new experimental oral swab TB test.
South Africa’s new National Strategic Plan for HIV, TB, and STIs is being developed this year. Spotlight editor Marcus Low asks what we should aim for in the new strategy and how we should go about developing it.
