Two years ago Orsmond TB Hospital in Nelson Mandela Bay closed its doors as a result of dwindling patient numbers. The closure made headlines for the fact that 45 staff members continued to be paid despite the closure. Luvuyo Mehlwana takes a closer look at both the situation at Orsmond and the wider trend of TB hospitals being closed or repurposed.
On September 22 ministers, heads of state, and other officials from around the world will gather in New York for the second United Nations High-Level Meeting on TB. Yet, a few months ago it was not the governments these officials represent, but two philanthropies that stepped in to ensure arguably the most important TB trial of the decade has the funding needed to proceed. Marcus Low contrasts commitments made at the previous UN High-Level Meeting on TB with recent data on funding for TB research and asks what this tells us about the state of the global response to an age-old killer.
Technical work on the discovery of new medicines is not commonly done in South Africa, or Africa, for that matter. One person who is at the forefront of changing this, is Kelly Chibale, a professor in organic chemistry and founder of the pioneering Holistic Drug Discovery and Development Centre – H3D – at the University of Cape Town. Biénne Huisman spoke to Chibale about his fascinating work and his journey from a village in Zambia, across the world, and back to Cape Town.
In March this year, the director-general of the Northern Cape government, Justice Bekebeke during a parliamentary oversight visit acknowledged that about 80% of the health facilities in the province did not meet their performance targets of finding people with tuberculosis and helping them complete treatment. Refilwe Mochoari looked at the statistics and spoke to several roleplayers about why the province is missing its TB targets.
In 1984, the then-head of Brooklyn Chest TB Hospital, Dr David Jenkin lamented inadequate services for TB patients, writing that “it is unflattering to realize that only war and pestilence appear able to bring more beds for TB sufferers”. Almost 40 years later, despite major scientific advances, TB hospitals like Brooklyn Chest remain important for treating complicated forms of the disease, where specialised healthcare staff can monitor medication interactions and side-effects. Biénne Huisman takes a look back at the hospital’s 151-year history and the difference it is making in the lives of children with TB today.
Every year, tens of thousands of people who fall ill with tuberculosis in South Africa are not diagnosed. Because of this, there has been much focus on testing people earlier rather than waiting for them to show up at clinics when they are already sick. One potential solution, explored in a trial called XACT 2, is community-based testing using a point-of-care molecular test. Tiyese Jeranji spoke to experts involved with XACT 2 and unpacks the study’s findings that were recently published in Nature Medicine.
People in South Africa who fall ill with tuberculosis (TB) often also have other health issues. HIV, which drives much of the TB epidemic in South Africa, is the most obvious co-infection, but people who fall ill with TB are also more likely to have diabetes and mental health problems than the general public. Tiyese Jeranji spoke to local experts about the interesting links between TB and liver problems.
While there is a long way to go, there has been important progress in South Africa’s response to tuberculosis (TB) and 2023 is set up to be a watershed year for the fight against the disease both globally and in South Africa. As we commemorate World TB Day, let us all pledge to make this year’s theme a reality – “Yes! You and I can end TB”, write Gaurang Tanna and Yogan Pillay.
The Mpumalanga Health Department plans to repurpose three TB hospitals due to dwindling numbers of in-patients at these hospitals. The hospitals – Bongani TB Hospital, Standerton TB Hospital, and Barberton TB Hospital – will be used for other health services. Nthusang Lefafa asked the department what prompted this and what it means for the TB response in the province.
South Africa’s National Department of Health is set to receive a donation of child-friendly formulations of several medicines used to treat drug-resistant tuberculosis (DR-TB). It is expected that over the next year the donation will spare roughly 200 children the substantial difficulties associated with taking DR-TB medicines meant for adults.
An HIV prevention injection approved in South Africa, several promising developments on the tuberculosis front, the National Health Insurance Bill grinding its way through Parliament, no end in sight to healthcare worker shortages, another dire year for health in Gauteng – Spotlight wraps up 2022 in under 1 000 words.
Diagnosing tuberculosis is difficult in people who struggle to cough up sputum samples – a particular problem in children and people living with HIV. One promising alternative to testing sputum is to test stool. Tiyese Jeranji unpacks the latest developments in this area.
