Antibiotic slashes risk of drug-resistant TB in kids, finds major SA study

Tuberculosis (TB) preventive therapy has been transformed in recent years, with treatment duration having been cut from six or more months to just three or one. Progress in developing new treatments to prevent drug-resistant forms of TB has however lagged behind, especially in children. Elri Voigt unpacks findings from a major new TB prevention study presented at the Union World Conference on Lung Health last week and plans for another important preventive therapy trial set to start soon.

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Interview: “Someone had to do it”, says SA TB activist on Time 100 list

At the age of 19 Phumeza Tisile contracted multidrug-resistant tuberculosis. For four years she battled the disease, losing her hearing in the process. At one stage, a doctor told her to visit a priest and prepare her soul for death. Recently, Tisile (now 33) made it on to TIME magazine’s 2023 TIME100 Next list, as one of 100 emerging leaders round the world who are “shaping the future and defining the next generation of leadership”. Sue Segar chatted to Tisile about her remarkable journey.

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Hospital histories: 151 years later, the drumming of little feet at Brooklyn Chest Hospital

In 1984, the then-head of Brooklyn Chest TB Hospital, Dr David Jenkin lamented inadequate services for TB patients, writing that “it is unflattering to realize that only war and pestilence appear able to bring more beds for TB sufferers”. Almost 40 years later, despite major scientific advances, TB hospitals like Brooklyn Chest remain important for treating complicated forms of the disease, where specialised healthcare staff can monitor medication interactions and side-effects. Biénne Huisman takes a look back at the hospital’s 151-year history and the difference it is making in the lives of children with TB today.

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Family focus shows promise for TB prevention

Tuberculosis (TB) preventive therapy is highly effective in preventing TB disease and death, yet only a few people have access to it. Tiyese Jeranji reports on how Médecins Sans Frontières (MSF) in Khayelitsha is helping TB patients, as well as their contacts, access preventive therapy in the comfort of their homes as part of a new family-centred TB care initiative.

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What is behind SA’s higher TB numbers?

A World Health Organization report published last week showed more people are falling ill with tuberculosis in South Africa than previously thought – but also that the country’s treatment success rate for dangerous drug-resistant forms of the disease have improved. Amy Green asks what’s behind these numbers.

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