Women in Health: Petro Terblanche – the farm girl from Brits who steered Africa’s first mRNA vaccine

Women in Health: Petro Terblanche – the farm girl from Brits who steered Africa’s first mRNA vaccine

When Professor Petro Terblanche joined biotechnology start-up Afrigen three years ago, she had no idea that the team she was heading up would create the continent’s first mRNA vaccine. But that wasn’t the first time Terblanche had been at the forefront of cutting-edge scientific work. Aisha Abdool Karim spoke to her as part of Spotlight’s Women in Health series.

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COVID-19: The role of next-generation vaccines in immunity

COVID-19: The role of next-generation vaccines in immunity

Indications are that the virus that causes COVID-19 is going to continue evolving and escaping the protection against infection people already have. Researchers are working on next-generation vaccines tailored to fight off specific versions of the virus, like the Omicron sub-lineages BA.4 and BA.5. But can these new vaccines be tested and produced fast enough to keep up with the rapidly changing virus? Aisha Abdool Karim asked some local experts.

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COVID-19: Reinfections amid ‘complex mix of immunity’

COVID-19: Reinfections amid ‘complex mix of immunity’

Omicron and its sub-variants have been dominating new surges of SARS-CoV-2 infections around the world and were behind South Africa’s fifth wave. The BA.4 and BA.5 sub-lineages unveiled yet more surprises about the evasive nature of these ever-emerging forms of SARS-CoV-2. They also hold clues for what to expect next and how to prepare. Aisha Abdool Karim reports.

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Monkeypox: Our top 10 questions  answered

Monkeypox: Our top 10 questions  answered

This week South Africa recorded its first case of monkeypox. Spotlight asked the experts and consulted WHO and NICD documents for answers to our top ten questions about monkeypox.

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Shorter, simpler DR-TB regimen expected later this year

Shorter, simpler DR-TB regimen expected later this year

A new six-month treatment regimen for drug-resistant forms of tuberculosis is expected to be rolled out in the public sector later this year – current regimens take anything from nine to 18 months. Catherine Tomlinson unpacks why the switch is important and outlines what still needs to happen to make it a reality.

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ANALYSIS: NHI Bill – clause-by-clause headbutting begins in Parliament

ANALYSIS: NHI Bill – clause-by-clause headbutting begins in Parliament

In what is expected to become a verbal minefield littered with the usual ideological quips, the members of Parliament’s Portfolio Committee on Health this week started the clause-by-clause deliberations on the National Health Insurance (NHI) Bill. Alicestine October assesses the first leg of the deliberations and issues set to pop up in the next round of deliberations, starting with clause 5 of the Bill next week.

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Editorial: How do we make an HIV and TB plan that has greater impact?

Editorial: How do we make an HIV and TB plan that has greater impact?

South Africa’s new National Strategic Plan for HIV, TB, and STIs is being developed this year. Spotlight editor Marcus Low asks what we should aim for in the new strategy and how we should go about developing it.

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In-depth: SA company gearing up to make API

In-depth: SA company gearing up to make API

While various medicines are produced in South Africa, the active pharmaceutical ingredients going into these medicines are mostly still imported. Catherine Tomlinson reports on a local company that is trying to change that – starting with active pharmaceutical ingredients for tuberculosis and COVID-19 medicines.

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In-depth: Landmark survey of key populations confirms scale of problems

In-depth: Landmark survey of key populations confirms scale of problems

People who belong to key populations, such as men who have sex with men, often report that it is difficult for them to access health services – for example, due to negative healthcare worker attitudes. Now, a large survey published last week by community healthcare monitoring group Ritshidze provides important statistics that not only confirm that such experiences are widespread but also help in pinning down some specific issues. Tiyese Jeranji reports.

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Interview: Prof Lynette Denny reflects on an extraordinary life of service

Interview: Prof Lynette Denny reflects on an extraordinary life of service

Professor Lynette Denny of the University of Cape Town recently received the Order of the Baobab, the country’s highest accolade for citizen excellence. Bienne Huisman spoke to her about her ground-breaking research in cervical cancer prevention, her own ongoing struggle with cancer, and the enrichment she has found in being of service.

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In-depth: The state of congenital syphilis in SA

In-depth: The state of congenital syphilis in SA

Over the last few years reported cases of congenital syphilis in South Africa have increased. This, accompanied by little or lack of notification, makes its management a challenge. Tiyese Jeranji reports on what congenital syphilis is, its management as well as gaps in management.

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New HIV/TB plan delayed by a year because of COVID-19

New HIV/TB plan delayed by a year because of COVID-19

South Africa will delay introducing a new HIV and TB plan until 2024, Deputy President David Mabuza revealed on Wednesday. The plan is delayed to allow the country’s HIV and TB responses to recover from COVID-19-related disruptions. Laura Lopez Gonzalez reports for Spotlight.

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