COVID-19: The role of next-generation vaccines in immunity

Indications are that the virus that causes COVID-19 is going to continue evolving and escaping the protection against infection people already have. Researchers are working on next-generation vaccines tailored to fight off specific versions of the virus, like the Omicron sub-lineages BA.4 and BA.5. But can these new vaccines be tested and produced fast enough to keep up with the rapidly changing virus? Aisha Abdool Karim asked some local experts.

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COVID-19: Reinfections amid ‘complex mix of immunity’

Omicron and its sub-variants have been dominating new surges of SARS-CoV-2 infections around the world and were behind South Africa’s fifth wave. The BA.4 and BA.5 sub-lineages unveiled yet more surprises about the evasive nature of these ever-emerging forms of SARS-CoV-2. They also hold clues for what to expect next and how to prepare. Aisha Abdool Karim reports.

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