A humanist with an unblinking gaze – Professor Ntobeko Ntusi takes the hot-seat at the South African Medical Research Council

Professor Ntobeko Ntusi may be softspoken, but he is not afraid to stand by his strongly held views. As he is set to take up the hot-seat at the country’s primary health research funder, he tells Spotlight’s Biénne Huisman about his background and his priorities for the new job.

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Vaginal ring to prevent HIV safe to use in late pregnancy and while breastfeeding

A vaginal ring used to prevent HIV infection is safe to use during late pregnancy and while breastfeeding, according to findings presented at a major international HIV conference in Seattle in the United States. The news comes as South Africa prepares for a likely national rollout of the ring and as more research confirms the safety of an HIV prevention pill during pregnancy. It is estimated that offering these products to pregnant and breastfeeding women could avert up to 136 000 new infections in roughly the next decade. Laura Lopez Gonzalez reports.

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Study suggests potential role for bnAbs in treating kids living with HIV

Broadly neutralising antibodies (bnAbs) are one of the most active and exciting areas in HIV research. Last year Spotlight reported on a “proof of concept” study showing that a specific bnAb can successfully prevent infection with certain strains of HIV. Now, we also have intriguing findings suggesting that bnAbs may have a role to play in the treatment of HIV in children. Elri Voigt reports.

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Why broadly neutralising antibodies might be the next big thing in HIV

We know antiretroviral therapy can prevent HIV infection, but can natural biological substances do the same? The results of a recent scientific trial have answered this question: Yes, using broadly neutralising antibodies. But what are broadly neutralising antibodies? How do they work? And when will the average person get access to them? Amy Green breaks down the science.

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Where are we in the race for a HIV vaccine?

While progress in the race for effective COVID-19 vaccines has been rapid and impressive, an effective HIV vaccine remains elusive. As part of Spotlight’s World AIDS Day 2020 coverage, Kathryn Cleary asks two of South Africa’s top vaccine researchers to update us on where we are in the race for an HIV vaccine.

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