Every year, tens of thousands of people who fall ill with tuberculosis in South Africa are not diagnosed. Because of this, there has been much focus on testing people earlier rather than waiting for them to show up at clinics when they are already sick. One potential solution, explored in a trial called XACT 2, is community-based testing using a point-of-care molecular test. Tiyese Jeranji spoke to experts involved with XACT 2 and unpacks the study’s findings that were recently published in Nature Medicine.
The South African TB Recovery Plan was developed to try and reverse the negative effects of the COVID-19 pandemic on the country’s TB response. On World TB Day, authors from TB Proof (a leading TB activist group) assess how the recovery is going and identify four key areas where further intervention is needed.
New tuberculosis infection guidelines released ahead of World TB Day are another important step in the right direction for South Africa’s TB response, argues Spotlight editor Marcus Low, while also warning of the substantial implementation challenges that remain.