Sub-clinical TB: Fascinating SA research helps push frontiers of TB science

Sub-clinical TB: Fascinating SA research helps push frontiers of TB science

While likely millions of people in South Africa have latent tuberculosis (TB) infection, only between three and 10% of these people ever fall ill with TB. Cutting-edge research conducted in South Africa has now taken us a significant step closer to a test that can predict who will and who will not fall ill with TB. Such a test, if simple and affordable, could potentially revolutionise TB prevention efforts.

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X-rays and AI could transform TB detection in SA, but red tape might delay things

X-rays and AI could transform TB detection in SA, but red tape might delay things

New World Health Organization guidance released this week endorses the wider use of chest X-rays and artificial intelligence for tuberculosis detection. Before these technologies can be fully utilised in South Africa, some regulatory and other issues will first have to be sorted out. Catherine Tomlinson reports.

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In-depth: Getting Gauteng’s HIV and TB response back on track

In-depth: Getting Gauteng’s HIV and TB response back on track

From March to July this year, the Gauteng Department of Health recorded 57 848 TB tests – a decrease of about 30 000 tests compared to the same period last year. The province performed better with HIV testing, although the HIV response has faltered in other areas. Melissa Javan makes sense of the province’s numbers and speaks to activists and community health workers about the impact of lockdown on their services and plans to get things back on track.  

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Eastern Cape government mum on TB plans and numbers

Eastern Cape government mum on TB plans and numbers

Numbers from the National Institute of Communicable Disease and from some provinces show that TB diagnoses have dropped dramatically in 2020 – likely due to COVID-19 and the related lockdown. The Eastern Cape Department of Health has however declined to share information on the TB situation in the province and their catch-up plans. Some activists are concerned about the situation. Luvuyo Mehlwana reports.

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TB catch-up plan underway in WC but old challenges linger

TB catch-up plan underway in WC but old challenges linger

In 2019 around 360 000 people in South Africa fell ill with tuberculosis (TB) and about 58 000 people died due to the disease, according to a World Health Organization Report released last week. The COVID-19 pandemic has exacerbated these already alarming numbers, with some TB patients stopping treatment during lockdown. Siyabonga Kamnqa looks at the plans the Western Cape Health Department has in place to get its TB programme back on track and finds old challenges still remain.

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TB treatment time cut by a third

TB treatment time cut by a third

A new four-month treatment course for drug-sensitive tuberculosis (the most common form of TB by far) is as safe and effective as the current six-month treatment course that has been in use since the 1980s, according to findings from a large new study. Amy Green reports.

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WHO estimates 20% more TB cases in SA than previously thought

WHO estimates 20% more TB cases in SA than previously thought

Around 20% more people are falling ill with tuberculosis (TB) in South Africa, than previously thought. This emerged from new estimates contained in the 2020 WHO World TB Report launched today.

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COVID-19: The fascinating science of what happens in the lungs

COVID-19: The fascinating science of what happens in the lungs

People with COVID-19 and people with tuberculosis (TB) can experience similar symptoms such as coughing and breathing difficulties as both diseases affect the lungs. Exactly how these diseases affect the lungs, however, differs. Tiyese Jeranji spoke to a leading South African pulmonologist to learn more.

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Some TB patients still required to take pills in front of witnesses

Some TB patients still required to take pills in front of witnesses

Some tuberculosis patients in South Africa are still required to take their pills in front of a healthcare worker or family member. Is this a justified means of ensuring people take their medicine, or is it an invasion of personal autonomy? Elri Voigt asked local TB experts.

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Opinion: Release of SA’s first National TB Prevalence Survey should not be delayed any longer

Opinion: Release of SA’s first National TB Prevalence Survey should not be delayed any longer

Even though it has been ready for months, findings of a critically important tuberculosis survey have not been made public. Every day that passes, the more outdated the findings become, and accordingly the less useful.

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Drop in DR-TB detection points to “crisis” in SA’s TB response

Drop in DR-TB detection points to “crisis” in SA’s TB response

A leading TB doctor says that “it is no exaggeration to say there is a TB crisis in the country”, and that “the impact of this crisis could be even more devastating than COVID-19”. Kathryn Cleary explores the COVID-19 pandemic’s impact on South Africa’s TB response and the way forward.

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