The complex interplay between TB and liver problems

People in South Africa who fall ill with tuberculosis (TB) often also have other health issues. HIV, which drives much of the TB epidemic in South Africa, is the most obvious co-infection, but people who fall ill with TB are also more likely to have diabetes and mental health problems than the general public. Tiyese Jeranji spoke to local experts about the interesting links between TB and liver problems.

Read More

XACT III: A trial asking how to take TB tests to the people

Roughly two in five people newly ill with TB worldwide are never diagnosed. In South Africa, this amounts to about 120 000 to 160 000 people per year. A large new study called XACT III is testing ways in which more people can be diagnosed and started on TB treatment more quickly. Tiyese Jeranji reports.

Read More

Opinion: Six ways clinics can help turn the tide on TB infection

Six simple interventions are at the heart of how clinics can be part of turning the tide on TB infection. By following a checklist of good practice, clinics can be safer for patients and staff. However, most clinics are failing to implement enough of these measures, putting people at risk of getting TB while waiting at the clinic, argues representatives from the community clinic monitoring group Ritshidze.

Read More

Opinion: World TB Day – let’s seize this moment to change the status quo

Like with SARS-CoV2, we need to rapidly implement and scale-up effective tuberculosis (TB) prevention interventions, while remaining adaptive to prevailing needs across the country. If we choose to pursue this more deliberate approach to TB prevention in South Africa, World TB Day will no longer be an admission of insufficient progress, but a celebration of defeating our long-standing battle with this curable disease, writes Dr Kavindhran Velen and Professor Salome Charalambous.

Read More

Tens of thousands of people with TB in SA not diagnosed, survey

Over 150 000 people who had TB in South Africa in 2018 were not diagnosed, according to findings from South Africa’s long-awaited National Tuberculosis Prevalence Survey. One reason for this is that an unexpectedly high number of people do not show the typical TB symptoms and are never x-rayed. Amy Green reports.

Read More

Sub-clinical TB: Fascinating SA research helps push frontiers of TB science

While likely millions of people in South Africa have latent tuberculosis (TB) infection, only between three and 10% of these people ever fall ill with TB. Cutting-edge research conducted in South Africa has now taken us a significant step closer to a test that can predict who will and who will not fall ill with TB. Such a test, if simple and affordable, could potentially revolutionise TB prevention efforts.

Read More

X-rays and AI could transform TB detection in SA, but red tape might delay things

New World Health Organization guidance released this week endorses the wider use of chest X-rays and artificial intelligence for tuberculosis detection. Before these technologies can be fully utilised in South Africa, some regulatory and other issues will first have to be sorted out. Catherine Tomlinson reports.

Read More