OPEN LETTER | Minister of Health Joe Phaahla, make TB a political priority

OPEN LETTER | Minister of Health Joe Phaahla, make TB a political priority

In this open letter to Minister of Health Dr Joe Phaahla, TB activists call for the disease to be made a political priority and demand multisectoral departmental accountability. They outline six demands for implementation by the end of this year. The letter was submitted on the final day of the South African TB Conference being held this week in Durban.

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Slow progress after decision to make TB prevention pills more widely available

Slow progress after decision to make TB prevention pills more widely available

Besides preventing illness and death, tuberculosis prevention therapy is estimated to be highly cost effective. Yet, uptake of the medication is not what it could be in South Africa. Tiyese Jeranji asks how much has changed since the Department of Health last year decided to make TB prevention therapy much more widely available.

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What we can learn about TB at the autopsy table

What we can learn about TB at the autopsy table

In addition to shedding light on what people actually die of, autopsies can also play an important role in helping us to better understand disease. Tiyese Jeranji unpacks tuberculosis-related autopsy research in the Western Cape and delves into some of the fascinating complexities of this branch of TB research.

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‘Let’s unite to end TB’ – a community-led approach can help wipe out TB in SA

‘Let’s unite to end TB’ – a community-led approach can help wipe out TB in SA

World TB Day is marked in the same week that South Africa celebrates Human Rights Day. A human rights based approach to TB mirrors a public health approach, argue Ingrid Schoeman, Sasha Stevenson, Janet Giddy, Renier Coetzee, and Petula Pienaar.

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New TB drug shows promise, but experimental vaccine disappoints

New TB drug shows promise, but experimental vaccine disappoints

While three new tuberculosis (TB) medicines have been registered in South Africa over the last decade, TB treatment still comes with several side effects and requires taking multiple different medicines, typically for six or more months. The search for better TB medicines got a boost last week with the presentation of promising findings from a study conducted in South Africa on an experimental drug called quabodepistat. Elri Voigt reports on this and other TB studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Denver, Colorado.

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EDITORIAL | With elections and NHI, this is a big year for healthcare in SA

EDITORIAL | With elections and NHI, this is a big year for healthcare in SA

South Africa is barrelling towards its most consequential and most competitive national and provincial elections since 1994. Spotlight editor Marcus Low asks what is on the line in these elections from a healthcare perspective and argues that the stakes are particularly high when it comes to NHI and the Gauteng and KwaZulu-Natal provincial health departments.

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Analysis: SA close to meeting TB research funding targets, but most countries falling short

Analysis: SA close to meeting TB research funding targets, but most countries falling short

South Africa is one of only six countries to ever meet their “fair share target” for funding tuberculosis (TB) research, according to a new report. In absolute terms however, South Africa’s contribution is small change compared to investments into TB research made by the top two contributors, the United States government and the Bill and Melinda Gates Foundation. Catherine Tomlinson unpacks what the report tells us about investment in TB research in South Africa.

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Antibiotic slashes risk of drug-resistant TB in kids, finds major SA study

Antibiotic slashes risk of drug-resistant TB in kids, finds major SA study

Tuberculosis (TB) preventive therapy has been transformed in recent years, with treatment duration having been cut from six or more months to just three or one. Progress in developing new treatments to prevent drug-resistant forms of TB has however lagged behind, especially in children. Elri Voigt unpacks findings from a major new TB prevention study presented at the Union World Conference on Lung Health last week and plans for another important preventive therapy trial set to start soon.

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Interview: “Someone had to do it”, says SA TB activist on Time 100 list

Interview: “Someone had to do it”, says SA TB activist on Time 100 list

At the age of 19 Phumeza Tisile contracted multidrug-resistant tuberculosis. For four years she battled the disease, losing her hearing in the process. At one stage, a doctor told her to visit a priest and prepare her soul for death. Recently, Tisile (now 33) made it on to TIME magazine’s 2023 TIME100 Next list, as one of 100 emerging leaders round the world who are “shaping the future and defining the next generation of leadership”. Sue Segar chatted to Tisile about her remarkable journey.

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