Behind the scenes: How the first 500 000 vaccine doses administered in SA were secured

When South Africa’s rollout of the AstraZeneca vaccine was put on hold in early February, a scramble ensued to ensure healthcare workers could be protected. Chris Bateman spoke to Professor Glenda Gray about the behind-the-scenes negotiations that helped secure 500 000 doses of the Johnson & Johnson vaccine – almost all of which have now been used in the Sisonke study.

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How to vaccinate millions as quickly as possible

Starting now, hundreds of thousands of COVID-19 vaccines will be arriving in South Africa weekly. Rather than spending energy and resources policing who gets them, we should be focusing on getting the vaccines as fast as possible into willing arms. Don’t try to micro-manage the rollout, writes Nathan Geffen and Marcus Low.

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COVID-19: Is the Free State ready for a third wave?

COVID-19 numbers have in recent weeks been rising in the Free State, leading some to fear that the province might be at the beginning of a third wave of infections. Refilwe Mochoari asked the Department of Health, unions, and opposition political parties whether the province is ready for a third wave.

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How vaccine safety is monitored in SA

Strict monitoring and surveillance systems for the safety of all vaccines, including those for COVID-19, are in place during vaccine trials as well as once vaccines are rolled out more widely. Adele Baleta takes a look at how vaccine-related adverse events are monitored in South Africa.

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Editorial: Pieces finally slotting into place for mass vaccination in SA

Within the next month or so we will be switching gears from the comparatively small-scale trial run of Sisonke to a full-on mass vaccination programme. As with the onset of a new wave of infections, this presents a dramatic shift in the pandemic and our response to it – although in this case, the shift is finally a good thing, writes Spotlight editor Marcus Low.

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In-depth: Promising signs for local biopharmaceutical production

Biopharmaceuticals are therapeutic drugs, vaccines, and diagnostics in which the active ingredient is produced in a living substance such as eggs or tobacco plants. The living substance acts as a ‘miniature factory’ in which the active ingredient is grown and replicated. Catherine Tomlinson takes a deep dive into the fascinating research and other initiatives in South Africa aimed at spurring local production of these products – and asks why a Cape Town-based company opted to set up a manufacturing plant in Mauritius rather than at home.

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