COVID-19: Will vaccinated people in South Africa need booster shots?

The two vaccines used in South Africa’s vaccination programme, those from Johnson & Johnson and Pfizer/BioNTech, have both been shown to be highly effective against COVID-19, particularly in preventing hospitalisation and death. But protection may wane over time and new variants may or may not render these vaccines less effective. Adele Baleta unpacks what we do and do not know about the potential need for booster shots and surveys some of the studies that will help fill the gaps.

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Editorial: Government should explain plans in wake of J&J setback

Jabs from Johnson & Johnson were central to plans to scale up South Africa’s COVID-19 vaccination programme. With news that a first consignment of two million doses cannot be used, it is critical that government play open cards with the public about its revised vaccination plans and timelines and what steps it is taking to procure more vaccines faster.

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How vaccine safety is monitored in SA

Strict monitoring and surveillance systems for the safety of all vaccines, including those for COVID-19, are in place during vaccine trials as well as once vaccines are rolled out more widely. Adele Baleta takes a look at how vaccine-related adverse events are monitored in South Africa.

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Editorial: Pieces finally slotting into place for mass vaccination in SA

Within the next month or so we will be switching gears from the comparatively small-scale trial run of Sisonke to a full-on mass vaccination programme. As with the onset of a new wave of infections, this presents a dramatic shift in the pandemic and our response to it – although in this case, the shift is finally a good thing, writes Spotlight editor Marcus Low.

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Opinion: WTO waiver is important, but so is fixing SA’s outdated patent laws

The World Trade Organization TRIPS council is expected to vote on South Africa and India’s proposed patent waiver on 10 or 11 March which could, if granted, help countries to scale up production of COVID-19 vaccines. But, while the waiver is important, argues Julia Chaskalson, it is also urgent that South Africa should amend its outdated domestic patent laws.

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Analysis: How do you price a life-saving vaccine during a pandemic?

In late January, Dr Anban Pillay, Deputy Director-General in South Africa’s National Department of Health, revealed that South Africa would pay more than double the price paid by the European Union (EU) for AstraZeneca’s COVID-19 vaccine. This set off a flurry of questions on how vaccine prices are set and why, in many cases, the prices themselves are not known to the public. Catherine Tomlinson takes a closer look at the issues involved.

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