How vaccine safety is monitored in SA

Strict monitoring and surveillance systems for the safety of all vaccines, including those for COVID-19, are in place during vaccine trials as well as once vaccines are rolled out more widely. Adele Baleta takes a look at how vaccine-related adverse events are monitored in South Africa.

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Analysis: The politics and promise behind a proposed pandemic treaty

25 heads of state, including South Africa’s President Cyril Ramaphosa, have called for the creation of an international pandemic treaty to strengthen global capacity to predict and respond to pandemic threats. But what should we make of this development, given that existing treaties have often been ignored during the COVID-19 crisis and recent efforts toward a research and development treaty for health products have floundered, asks Catherine Tomlinson.

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Editorial: Pieces finally slotting into place for mass vaccination in SA

Within the next month or so we will be switching gears from the comparatively small-scale trial run of Sisonke to a full-on mass vaccination programme. As with the onset of a new wave of infections, this presents a dramatic shift in the pandemic and our response to it – although in this case, the shift is finally a good thing, writes Spotlight editor Marcus Low.

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Analysis: How do you price a life-saving vaccine during a pandemic?

In late January, Dr Anban Pillay, Deputy Director-General in South Africa’s National Department of Health, revealed that South Africa would pay more than double the price paid by the European Union (EU) for AstraZeneca’s COVID-19 vaccine. This set off a flurry of questions on how vaccine prices are set and why, in many cases, the prices themselves are not known to the public. Catherine Tomlinson takes a closer look at the issues involved.

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Tens of thousands of people with TB in SA not diagnosed, survey

Over 150 000 people who had TB in South Africa in 2018 were not diagnosed, according to findings from South Africa’s long-awaited National Tuberculosis Prevalence Survey. One reason for this is that an unexpectedly high number of people do not show the typical TB symptoms and are never x-rayed. Amy Green reports.

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400 people in SA with highly drug-resistant TB to get new three-drug regimen

Treating highly drug-resistant forms of tuberculosis can take anything from nine to 24 months and patients have to contend with various unpleasant, and sometimes dangerous, side effects. A new six-month regimen made up of just three drugs that will be offered to 400 patients in South Africa might offer a better solution for some. Tiyese Jeranji reports.

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COVID-19: How vaccine registration will work in SA

Before any COVID-19 vaccines can be made available in South Africa, they must be authorised by South Africa’s medicines regulator—the South African Health Products Regulatory Authority (SAHPRA). Catherine Tomlinson explores how SAHPRA is preparing to review and authorise the use of COVID-19 vaccines in the country and the different authorisation approaches they may use.

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Finding the money: The case for raising the Health Promotion Levy

The recent budget policy statement shows South Africa finds itself in a very tight fiscal space where it has to navigate a global pandemic along with other health challenges such as rising rates of non-communicable diseases. Russell Rensburg argues that the Health Promotion Levy should be increased to 20% – which will raise much-needed revenue that will contribute to preventing disease and reducing healthcare costs.

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What is behind SA’s higher TB numbers?

A World Health Organization report published last week showed more people are falling ill with tuberculosis in South Africa than previously thought – but also that the country’s treatment success rate for dangerous drug-resistant forms of the disease have improved. Amy Green asks what’s behind these numbers.

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