New drug offers hope against untreatable gonorrhoea

Newly announced results of a pivotal phase 3 trial have demonstrated the effectiveness of a new treatment for gonorrhoea. The medicine, zoliflodacin, is the first new drug developed to treat gonorrhoea in over 30 years. More than half of the 930 patients in the trial were from South Africa. Catherine Tomlinson reports.

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Face to Face: Prof Helen Rees on SAHPRA, women’s rights, and her appetite for justice

As a rebellious teenager growing up in the British town of Harpenden, Professor Helen Rees would sneak out to attend anti-apartheid talks. Today, she is a renowned scientist and chair of South Africa’s medicines regulator. Biénne Huisman chatted to Rees about her career, prioritising women’s reproductive health, and her role at the South African Health Products Regulatory Authority.

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In-depth: What contraceptives are available in SA and which ones are most popular?

There are a variety of tools available today to prevent pregnancy including pills, intrauterine devices, subdermal implants, injections, condoms, male and female sterilisation, and emergency contraception. Statistics suggest that people in South Africa do, in principle at least, have access to and are aware of these contraceptive methods, albeit not at the desired levels. Elna Schütz looks at what contraceptive methods are available and makes some surprising discoveries along the way about which ones are most popular.

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HPV: What is happening with SA’s other relatively new vaccine programme?

In 2014, South Africa launched an HPV vaccination campaign targeting 9-year-old public school learners in Grade 4. It involves delivering two doses of vaccine six months apart. Laura Owings asks how the campaign is going and what recent real-world HPV vaccine effectiveness data from the United Kingdom might mean for South Africa.

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In-depth: What we know about SA’s rampant gonorrhoea epidemic

Despite the global emergence of highly resistant strains of gonorrhoea, including untreatable variants, a new antibiotic for the disease has not been developed in over half a century. In January, a trial began in South Africa and other countries for a new gonorrhoea antibiotic. But what is gonorrhoea? How significant is the problem in South Africa and among those living with HIV? Do we have resistant strains too? Experts report a grim situation, but with hope on the horizon. Amy Green reports.

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U=U: We should put people living with HIV at the centre of HIV prevention efforts

The U=U campaign is based on a simple message – an undetectable viral load in people living with HIV equals an untransmissible virus. The U=U campaign, argues Mandisa Dukashe, has the power to motivate people living with HIV to adhere to ARVs, achieve viral suppression, and subsequently lead long and healthy lives while preventing HIV transmission to sexual partners and their babies.

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