Widely used HIV drug in SA flagged for reports of resistance – but experts say don’t panic

That HIV can develop resistance to the drugs used to treat it is nothing new, but results from recent studies reveal the emergence of resistance in subsets of people living with HIV to dolutegravir – an antiretroviral widely used in South Africa. Top HIV experts spoke to Elri Voigt about the new findings and what it means for people living with HIV in the country.

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Obesity and HIV: Semaglutide should be rolled out in SA, says Dr Nomathemba Chandiwana

Obesity is a public health crisis in South Africa, similar to HIV in the late 1990s, Dr Nomathemba Chandiwana tells Spotlight on the sidelines of the Conference on Retroviruses and Opportunistic Infections (CROI) in Denver, Colorado. She also presented research that found lifestyle behaviour changes had a limited effect on reversing weight gain in people living with HIV.

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New TB drug shows promise, but experimental vaccine disappoints

While three new tuberculosis (TB) medicines have been registered in South Africa over the last decade, TB treatment still comes with several side effects and requires taking multiple different medicines, typically for six or more months. The search for better TB medicines got a boost last week with the presentation of promising findings from a study conducted in South Africa on an experimental drug called quabodepistat. Elri Voigt reports on this and other TB studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Denver, Colorado.

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SA company set to manufacture HIV prevention ring

A company headquartered in Johannesburg will start making flexible silicone rings to protect women from HIV. The move signals a strong vote of confidence in an African firm to supply the ring at adequate scale and affordable prices, and a crucial step to making the continent self-reliant, reports Catherine Tomlinson.

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There is a ‘worrying’ resurgence of sexually transmitted infections in Gauteng

There’s a resurgence of sexually transmitted infections (STIs) in South Africa and around the world. The Gauteng Department of Health recently reported an increase of newly acquired STIs, in particular gonorrhoea and chlamydia. This spike in cases call for management guidelines and awareness programmes to be reviewed, reports Ufrieda Ho.

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EDITORIAL | With elections and NHI, this is a big year for healthcare in SA

South Africa is barrelling towards its most consequential and most competitive national and provincial elections since 1994. Spotlight editor Marcus Low asks what is on the line in these elections from a healthcare perspective and argues that the stakes are particularly high when it comes to NHI and the Gauteng and KwaZulu-Natal provincial health departments.

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