Broadly neutralising antibodies (bnAbs) are one of the most active and exciting areas in HIV research. Last year Spotlight reported on a “proof of concept” study showing that a specific bnAb can successfully prevent infection with certain strains of HIV. Now, we also have intriguing findings suggesting that bnAbs may have a role to play in the treatment of HIV in children. Elri Voigt reports.
HIV and ageing were one of the hot topics at the recently held Conference on Retroviruses and Opportunistic Infections. Elri Voigt reports.
A new study has analysed the change in the rate of new HIV infections from 2010 to 2019 and found that HIV incidence in South Africa has halved since 2010. This is mainly due to antiretroviral treatment and condom promotion, but male medical circumcision and behaviour change after HIV diagnosis had a role too, writes Leigh Johnson.
The top priority in our HIV programme should be to make it as easy as possible for people to start and stay on treatment. Yet, as a number of provincial reports released this year by community monitoring group Ritshidze have shown, there are many healthcare system factors that work directly against this objective. Spotlight editor Marcus Low considers some of the potential solutions.
Children living with HIV have to take multiple different antiretroviral pills or syrups twice a day, while most adults in South Africa have been offered one pill once a day regimens for around a decade. At the recent South African HIV Clinicians Society (SAHCS) conference, various speakers argued that better treatment regimens for kids are needed urgently. Thabo Molelekwa reports.
Studies show that people living with HIV are often at a higher risk for depression and anxiety, including a higher risk of suicide. Tiyese Jeranji spoke to mental health practitioners, activists, and people living with HIV to unpack the link between HIV and mental health.
Findings of a clinic monitoring report released last week, again highlighted how delivery of health services in the Eastern Cape are hamstrung by staff and medicine shortages. Luvuyo Mehlwana unpacks the data and the provincial health department’s plans to address the challenges identified in the report.
An antiretroviral injection administered every two months has been shown to be highly effective in preventing people from getting HIV in two large trials. Catherine Tomlinson asks what needs to happen before these injections become available to people in South Africa.
The risk of developing severe or fatal COVID-19 is 30% greater in people living with HIV compared to those who are HIV negative, according to a new report from the World Health Organization. Comprised of data from 37 countries, including South Africa, the report suggests people living with HIV should be prioritised for vaccination. Laura Owings reports.
In what Spotlight understands to be a world-first, South Africa is on the brink of allowing pharmacists with the required permits to prescribe HIV medicines without people first having to get a script from a doctor or nurse. Catherine Tomlinson investigates how it will work and why it may be just the boost the country’s HIV response needs.
Cryptococcal meningitis is the second biggest killer of people living with HIV after tuberculosis (TB). Now, a global initiative, the Ending Cryptococcal Meningitis Deaths by 2030 Strategic Framework aims to get the gold standard drug to treat cryptococcal meningitis – flucytosine – registered in countries that need it. Amy Green reports.
The growing crisis in many of South Africa’s clinics has reached a point where patient care is being compromised and there is a deepening worry that people living with HIV are being pushed out of treatment, argues Anele Yawa and Lotti Rutter. In this op-ed, they ask whether repeat prescription collection strategies are simpler and quicker than waiting in long clinic queues.
