COVID-19: What next as shots expire and become harder to get?

Millions of doses of the Pfizer-BioNtech COVID-19 vaccine procured by the South African government have expired and the shot is largely unavailable to people in the country. Meanwhile, earlier this month, the World Health Organization declared an end to the COVID-19 ‘Public Health Emergency of International Concern’. Adele Baleta asks what all this means for COVID-19 in South Africa.

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Courts to decide whether pharmacists can start HIV medicines without a doctor’s script

In August 2021, the South African Pharmacy Council published legislation in the Government Gazette to enable pharmacists to prescribe and dispense antiretroviral medicines for the treatment and prevention of HIV. A legal challenge then put the brakes on the initiative and the courts are now set to decide whether it can continue. Catherine Tomlinson reports.

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Supply issues delaying wider rollout of shorter TB preventive therapy

South Africa’s recently published guidelines for the treatment of tuberculosis (TB) infection have been welcomed by several experts. Among others, the guidelines endorse the use of a three-month course of TB preventive therapy as opposed to the old six-month course. But, while the intention is to roll out the three-month course quite widely, supply constraints may delay things. Tiyese Jeranji reports.

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Analysis: Landmark SA court case takes on US maker of cystic fibrosis drugs

Cystic fibrosis (CF) is a debilitating and often deadly disease. Until recently, the only treatments for its symptoms were difficult to administer and time-consuming. Life-changing new treatments that dramatically improve the prognosis for people with the disease have been developed, but they are expensive and Vertex, the US company making the drugs, has decided against registering the drugs in South Africa. Cheri Nel, a woman living with CF, is now taking Vertex on in a South African court. Catherine Tomlinson unpacks the details.

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Analysis: Why has the price of this cancer medicine risen and fallen by over a thousand percent since 2016?

Lenalidomide is an important medicine used for the treatment of multiple myeloma – a type of bone marrow cancer that is not curable and typically requires long-term, ongoing treatment. Over the last decade, the price of this drug has fluctuated dramatically in South Africa and patients and their doctors have gone to extreme lengths to access it. Catherine Tomlinson unpacks the remarkable recent history of lenalidomide.

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Analysis: How well did SAHPRA do in 2022?

The South African Health Products Regulatory Authority has often made the headlines in recent years – be it in relation to COVID-19 vaccines, access to ivermectin, the approval of an HIV prevention injection, or most recently the clearing of inherited backlogs. Catherine Tomlinson assesses the state of South Africa’s medicines regulator as 2022 draws to a close.

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Editorial: World AIDS Day 2022 – Choice, convenience, and respect should be the cornerstone of SA’s HIV response

In Spotlight’s analysis of South Africa’s HIV response in recent years, two issues have stood out consistently – still too many people living with HIV are not taking antiretroviral therapy and the rate of new HIV infections in South Africa is not coming down fast enough. Accordingly, argues Spotlight editor Marcus Low, we must accelerate the shift toward an HIV response where we make testing for HIV and taking antiretroviral treatment as convenient as possible.

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