HIV vaccine research set to change focus in wake of Mosaico disappointment

Top South African HIV clinicians are setting their sights on different approaches to finding an HIV vaccine after the “disappointing” news that the Mosaico trial was stopped early because the vaccine did not show any efficacy. The search for an HIV jab now seems set to pivot from vaccines that induce T-cell immunity to ones that induce B-cell immunity. Adele Baleta unpacks what that means and the reasoning behind it.

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