SA is one step closer to a new TB vaccine, but there is a lot of work ahead

In March 2024, a pivotal clinical trial was launched to evaluate what might well become the first new tuberculosis vaccine on the market in more than a century. As anticipation mounts for the trial to deliver results, Russell Rensburg argues that we need to start preparing for a rollout of the jab, but that we should think of preparation more widely than just the technicalities of regulatory approval and drug supply.

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In The Spotlight | What are broadly neutralising antibodies and what do they mean for the fight against HIV?

HIV is known for its ability to outsmart our immune system’s normal defences. A small number of people living with HIV are however able to generate more effective immune responses to HIV. In this special briefing, Catherine Tomlinson zooms in on broadly neutralising antibodies, the secret sauce in these immune responses.

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Inside The Box with Dr Andy Gray | Are complementary medicines effectively regulated in South Africa?

The regulation of complementary and alternative medicines in South Africa has been hotly contested in recent decades, including in court rooms. In his latest column for Spotlight, Dr Andy Gray unpacks the legal background and the current state of this still unfolding regulatory saga.

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What the Public Protector’s food safety investigation reveals about Gauteng’s public health early warning system

From inspecting spaza shops to monitoring water quality, Environmental Health Practitioners help prevent disease before outbreaks occur. A Public Protector investigation reveals why Gauteng municipalities are struggling to deliver these essential public health services. The investigation also helps clarify what will be at stake in South Africa’s local government elections in November. Christina Pitt reports.

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Reforming prescribed minimum benefits is the first step to affordable medical cover

With plans in motion to roll out universal health coverage in South Africa, Dr Katlego Mothudi, of the Board of Healthcare Funders, argues that revising the compulsory prescribed minimum benefits that medical schemes must provide can be a tool to deliver meaningful improvements today while laying the foundations for a more sustainable healthcare system tomorrow.

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AIDS 2026: Some pieces falling into place for monthly HIV prevention pill, but key data not yet in

If an HIV prevention pill that provides a month of protection at a time performs well in two ongoing clinical trials, it could become the next big thing in HIV prevention after the lenacapavir injection. A new licensing agreement is paving the way for South Africa’s Aspen Pharmacare to produce the pill should the study findings be positive and the drug be registered.

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