In-depth: Use of urine test for TB increasing

In 2015, the World Health Organization recommended a urine test that helps with the detection of tuberculosis (TB) in people living with HIV who are hospitalised or who have compromised immune systems. While uptake of this test in South Africa was initially quite slow, numbers presented at the recent South African TB Conference suggest that the use of the test is now increasing. Tiyese Jeranji reports.

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Women in Health: Francesca Conradie – from HIV to groundbreaking TB research

Dr Francesca Conradie knew she wanted to be a doctor when she was eight years old. Now, 50 years later, she is a pioneer in the field of tuberculosis (TB) and led a landmark trial that changed how drug-resistant TB is treated. Aisha Abdool Karim spoke to her about the reasons behind her switch from HIV research to TB, her initial surprise at the remarkable NiX trial results, and the man who has shaped her life – her father.

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Positive signs for new TB testing strategy

Under a new tuberculosis (TB) diagnosis strategy, people considered to be at high risk of TB are offered molecular TB tests, even if they do not have any symptoms. A landmark study in 2020 showed that such a strategy can help diagnose more people more quickly. Now, early indications are that it also works in the real world and South Africa’s lab service says they can cope with the increased demand. Tiyese Jeranji reports.

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Are oral swabs the future of TB testing?

The World Health Organization estimates that every year 40% of people who fall ill with TB globally are not diagnosed. There is thus an urgent need for faster, safe, and more convenient TB tests. The current gold standard for testing still requires people to cough up sputum, something that some people and children, in particular, struggle with. Tiyese Jeranji looks at the potential of a new experimental oral swab TB test.

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Profile: Keertan Dheda – reflections on a career finding ways to fight TB

Professor Keertan Dheda has come a long way from growing up as one of three siblings in a one-bedroom apartment in a high-rise in central Durban. Biénne Huisman chatted to Dheda, now the head of the University of Cape Town’s Division of Pulmonology, and a Professor in Mycobacteriology and Global Health at the London School of Hygiene and Tropical Medicine, about work-life balance, problem-solving that excites him, and a career dedicated to the fight against tuberculosis.

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What should the TB priorities be in the new NSP?

The period covered by South Africa’s National Strategic Plan (NSP) for HIV, TB, and STIs 2017 – 2022 will soon come to an end. Against the backdrop of another World TB Day, Tiyese Jeranji asked several local tuberculosis experts what they think the TB priorities should be as South Africa develops an NSP for the next five years.

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