The second United Nations High-Level Meeting on Tuberculosis is taking place in New York today. Sihle Mahonga Ndawonde argues that better TB data and more transparency are needed in South Africa if we are to get and stay on the road to meeting the ambitious targets set and endorsed at this UN meeting.
Professor Valerie Mizrahi, a world-leading tuberculosis researcher and director of the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town, is retiring at the end of the year. Biénne Huisman sat down with Mizrahi to talk about her journey in TB research, passing the baton to a new generation of researchers, and how she helped build a research ecosystem that brings together specialists across the basic, clinical, and public health sciences.
On September 22 ministers, heads of state, and other officials from around the world will gather in New York for the second United Nations High-Level Meeting on TB. Yet, a few months ago it was not the governments these officials represent, but two philanthropies that stepped in to ensure arguably the most important TB trial of the decade has the funding needed to proceed. Marcus Low contrasts commitments made at the previous UN High-Level Meeting on TB with recent data on funding for TB research and asks what this tells us about the state of the global response to an age-old killer.
The modernist five-storey Mowbray Maternity Hospital sits on a swathe of Cape Town’s earliest contested colonial farm land, earmarked by Jan Van Riebeeck in 1657. Biénne Huisman visited the hospital to learn about its history and its continuing role in helping mothers and babies in the 21st century.
Tracing the close contacts of people ill with tuberculosis (TB) and offering them TB preventive therapy is part of South Africa’s strategy to fight TB. A recent analysis found that such an approach of tracing household contacts and providing them with TB preventive treatment is cost-effective and would – by 2025 – cut deaths by 35% among household contacts of all ages and people living with HIV. In light of these new findings, Tiyese Jeranji assesses the state of contact tracing in South Africa’s public healthcare system.
While there is limited data on tuberculosis (TB) in South Africa’s schools, a growing body of evidence suggests that there is indeed significant TB transmission taking place in the country’s often over-crowded classrooms. Tiyese Jeranji spoke to several local experts about what we do and do not know about the impact this age-old disease is having on our learners and their households.
During the COVID-19 pandemic, we saw the remarkable power of genomics in helping us keep track of new viral variants. Several scientists argue that Africa should continue to invest in genomics to support disease control and public health. Sue Segar asks what this means in practice and why it is considered so critically important.
People in South Africa who fall ill with tuberculosis (TB) often also have other health issues. HIV, which drives much of the TB epidemic in South Africa, is the most obvious co-infection, but people who fall ill with TB are also more likely to have diabetes and mental health problems than the general public. Tiyese Jeranji spoke to local experts about the interesting links between TB and liver problems.
South Africa has been using HIV Rapid Diagnostic Tests (Finger prick same-day testing) for years. Now, the National Department of Health has decided to align with the World Health Organization’s recommendation of a new three-test algorithm to ensure accuracy of results. René Sparks unpacks why this is important.
South Africa’s new National Strategic Plan for HIV, TB, and STIs 2023-2028 and the country’s TB Recovery Plan necessitate a sharp increase in TB testing and increased enrolment into care, which will require additional spending on testing and medicines. Sihle Mahonga Ndawonde argues that a joint committee should be set up to review and interrogate provincial departments’ resource allocation decisions for the next three years.
South Africa’s National Strategic Plan for HIV, TB and STIs (2023 – 2028) was launched on Friday at Tlhabane Stadium in Rustenburg, North West as the world commemorated World TB Day. Nthusang Lefafa attended the event and spoke to experts and activists about the state of TB and HIV and the work that lies ahead with the new NSP.
Despite advances in paediatric TB care, substantial challenges remain. If we are to heed the call for this year’s World TB Day – ‘Yes! We can end TB’ – we will need to significantly ramp up dedicated investment for an integrated approach to addressing TB in children, argues Dr Sipho Nyathi.
