In-depth: Promising signs for local biopharmaceutical production

Biopharmaceuticals are therapeutic drugs, vaccines, and diagnostics in which the active ingredient is produced in a living substance such as eggs or tobacco plants. The living substance acts as a ‘miniature factory’ in which the active ingredient is grown and replicated. Catherine Tomlinson takes a deep dive into the fascinating research and other initiatives in South Africa aimed at spurring local production of these products – and asks why a Cape Town-based company opted to set up a manufacturing plant in Mauritius rather than at home.

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In-depth: SA at cutting edge of TB vaccine research

It is a hundred years since the BCG vaccine, the only registered vaccine proven to offer some protection against tuberculosis (TB), was first used in people. Now researchers in South Africa are at the forefront of clinical trials testing experimental new TB vaccines. Adele Baleta reports.

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Opinion: World TB Day – let’s seize this moment to change the status quo

Like with SARS-CoV2, we need to rapidly implement and scale-up effective tuberculosis (TB) prevention interventions, while remaining adaptive to prevailing needs across the country. If we choose to pursue this more deliberate approach to TB prevention in South Africa, World TB Day will no longer be an admission of insufficient progress, but a celebration of defeating our long-standing battle with this curable disease, writes Dr Kavindhran Velen and Professor Salome Charalambous.

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Support for some TB patients just a phone call away

With just a tap of a finger, some people with drug-resistant tuberculosis can get in touch with a counsellor to get support over the phone. Tiyese Jeranji looks at a telephone support project that has helped keep some people with TB connected with their healthcare workers during the most difficult periods of the COVID-19 pandemic.

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Opinion: WTO waiver is important, but so is fixing SA’s outdated patent laws

The World Trade Organization TRIPS council is expected to vote on South Africa and India’s proposed patent waiver on 10 or 11 March which could, if granted, help countries to scale up production of COVID-19 vaccines. But, while the waiver is important, argues Julia Chaskalson, it is also urgent that South Africa should amend its outdated domestic patent laws.

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