Growing the beta variant – young scientist remembers the day they danced in the lab

During South Africa’s COVID-19 hard lockdown, rising star scientist Dr Sandile Cele spent his Christmas holidays in a laboratory. Soon the 35-year-old became the first to successfully grow the beta variant of SARS-CoV-2 in the lab. Biénne Huisman spoke to Cele about how he did this, the string of accolades he received since, and his leap from a modest upbringing to the global scientific stage.

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Feature: The complexities of traditional and medical circumcision in the Eastern Cape

While most male circumcisions performed in the Eastern Cape are done in the traditional manner, there are also significant numbers of medical male circumcisions being conducted. Siyabonga Kamnqa reports on this year’s winter initiation season in the province and the complex interplay between culture, safety, and protection against HIV involved in deciding between the two types of circumcision.

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Statin lowers cardio risk in people living with HIV, large study finds

Study findings presented this week at a major HIV conference show that taking a statin every day substantially reduces the chances of suffering a major adverse cardiovascular event in people living with HIV who have a low-to-moderate risk of cardiovascular disease. The findings were also published in the New England Journal of Medicine. Elri Voigt unpacks the study findings and asks what it might mean for people in South Africa.

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Opinion: HIV investments remain no-brainers, but some things need to change

HIV in South Africa is not the crisis it was 20 years ago, and the country faces a growing burden of non-communicable diseases, but specific investments in HIV nevertheless continue to offer excellent value for money for governments and donors alike. As people gather for the 2023 International AIDS Society Conference in Brisbane, Australia, Marcus Low argues that while funding for HIV interventions remains absolutely essential, it is also critical for the future of the HIV response and people living with HIV that HIV should now be better integrated with other healthcare services, especially those for diabetes and hypertension.

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Going viral: Dr Chivaugn Gordon on medical school with a difference

With humour and wearing an occasional wig, Dr Chivaugn Gordon teaches medical students about serious women’s health issues. During South Africa’s COVID-19-related hard lockdown she delighted students at the University of Cape Town by making educational videos using household items as props. Biénne Huisman asked Gordon about her creative take on medical training, her love of teaching, and sensitising students about intimate partner violence.

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In-depth: How big a problem is TB in SA’s schools?

While there is limited data on tuberculosis (TB) in South Africa’s schools, a growing body of evidence suggests that there is indeed significant TB transmission taking place in the country’s often over-crowded classrooms. Tiyese Jeranji spoke to several local experts about what we do and do not know about the impact this age-old disease is having on our learners and their households.

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In-depth: A tale of two make-do clinics in the rural Eastern Cape

The state of the Macacuma Clinic and the Ugie Clinic in the Eastern Cape came under the spotlight during the provincial legislature’s health committee visit from 10 to 14 October last year, when they visited several public health facilities in the Joe Gqabi District. Luvuyo Mehlwana recently went back to assess whether there has been any progress at the two facilities since the committee made its findings public.

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Over 4.7m people in SA placed on new HIV med in four years

In what is likely one of the largest treatment rollouts in South African history, well over four million people living with HIV have started taking the antiretroviral dolutegravir since its introduction around four years ago. Now, according to a recent study published in the Lancet medical journal, use of dolutegravir in South Africa is associated with more people staying on treatment and higher rates of viral suppression. Elri Voigt unpacks the study findings and assesses progress in the country’s switch to dolutegravir-based HIV treatment.

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In-depth: Breakthrough hepatitis C cures slowly becoming more widely available in South Africa

Almost a decade after they were first proven to be safe and highly effective, game-changing medicines to cure hepatitis C are finally becoming more widely available in South Africa. But not all the regulatory and other challenges behind the delay have yet been overcome and, as a result, access remains relatively limited for now. Catherine Tomlinson reports.

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In-depth: Children are still dying of malnutrition in the Free State

Even in 2023, infants under five years in the Free State are still dying from a lack of healthy food. From April to June this year, 21 children in the province died of severe acute malnutrition and one died of moderate acute malnutrition. Refilwe Mochoari unpacks the numbers and asks government about its plans to address what at least one expert is calling a ‘crisis’.

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