In-depth: How do long-acting HIV treatments work?

Researchers have been trying to develop antiretroviral medicines that can last for weeks, months or even years per dose. Two such long-acting formulations have been approved in South Africa, but several more are on the horizon. Elri Voigt explores the science behind what makes a formulation long-acting and takes a look at some particularly exciting prospects.

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In-depth: What new WHO TB numbers mean for SA

An estimated 54 000 people died of tuberculosis in South Africa in 2022 and around 280 000 fell ill with the disease, according to just-released figures from the World Health Organization. Catherine Tomlinson unpacks the figures and what they mean for the country’s TB response.

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Surgery backlog in Northern Cape getting worse

The surgical backlog in the Northern Cape appears to have ballooned in recent months. The province’s MEC for health says it is due to a lack of specialised theatre staff and delays related to the COVID-19 pandemic. Refilwe Mochoari reports on the latest figures and asks what the Northern Cape Department of Health is planning to do about the situation.

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Interview: “The situation is not going away,” says inspiring TB doctor

Dr Juli Switala (42) has treated children in Nigeria, helped fatally ill patients during the 2014 Ebola outbreak in Sierra Leone, and delivered babies at a hospital in Afghanistan against a backdrop of upheaval and violence. But nowhere cuts close to her heart quite like Brooklyn Chest – the tuberculosis (TB) hospital on Cape Town’s north-western fringes. Biénne Huisman chatted with Switala about her work in hospitals around the world, the challenges of treating kids with TB, and going for a run to get away from it all.

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New drug offers hope against untreatable gonorrhoea

Newly announced results of a pivotal phase 3 trial have demonstrated the effectiveness of a new treatment for gonorrhoea. The medicine, zoliflodacin, is the first new drug developed to treat gonorrhoea in over 30 years. More than half of the 930 patients in the trial were from South Africa. Catherine Tomlinson reports.

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In-depth: What government is doing to reduce medicines stockouts

Over the last decade, the National Health Department has rolled out a range of electronic surveillance systems to monitor medicine stocks throughout the country’s healthcare facilities, but stockouts persist due to a host of ongoing challenges. Jesse Copelyn takes a closer look at what is being done to ensure that our clinics and pharmacies do not run out of important medicines.

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In-depth: Will Eastern Cape Health reforms survive the change in leadership?

The Eastern Cape Department of Health have for years made headlines for the wrong reasons. A few weeks prior to her recent removal as head of the department, Dr Rolene Wagner made the case that the situation is being turned around. Tiyese Jeranji looks back at Wagner’s presentation at the Rural Health Conference in Chintsa and asks whether the reforms will continue in her absence.

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