Positive signs for new TB testing strategy

Under a new tuberculosis (TB) diagnosis strategy, people considered to be at high risk of TB are offered molecular TB tests, even if they do not have any symptoms. A landmark study in 2020 showed that such a strategy can help diagnose more people more quickly. Now, early indications are that it also works in the real world and South Africa’s lab service says they can cope with the increased demand. Tiyese Jeranji reports.

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Profile: Keertan Dheda – reflections on a career finding ways to fight TB

Professor Keertan Dheda has come a long way from growing up as one of three siblings in a one-bedroom apartment in a high-rise in central Durban. Biénne Huisman chatted to Dheda, now the head of the University of Cape Town’s Division of Pulmonology, and a Professor in Mycobacteriology and Global Health at the London School of Hygiene and Tropical Medicine, about work-life balance, problem-solving that excites him, and a career dedicated to the fight against tuberculosis.

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Analysis: Is SA on course to solve its TB diagnosis problem?

It is estimated that over 100 000 of the over 300 000 people who fall ill with TB in South Africa every year are not diagnosed. As a result, improving TB screening and testing has become a high priority in South Africa’s TB response. Coinciding with World TB Day 2022, Spotlight editor Marcus Low examines new information shared by the National Department of Health and assesses the state of the country’s TB case-finding efforts.

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Family focus shows promise for TB prevention

Tuberculosis (TB) preventive therapy is highly effective in preventing TB disease and death, yet only a few people have access to it. Tiyese Jeranji reports on how Médecins Sans Frontières (MSF) in Khayelitsha is helping TB patients, as well as their contacts, access preventive therapy in the comfort of their homes as part of a new family-centred TB care initiative.

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Fingerstick blood test shows promise for TB screening

The World Health Organization estimates that over four million of the almost ten million people who fell ill with tuberculosis in 2020 were not diagnosed. One obstacle to more people being diagnosed is the fact that most current tests require people to produce sputum – something children and some people living with HIV find difficult. Tiyese Jeranji looks at a new fingerstick blood test that may help diagnose more people quicker.

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Opinion: Quality Tuberculosis care starts with people

The world is seeing tuberculosis (TB) deaths increase for the first time in over a decade. To turn things around and to put an end to TB being a leading infectious disease killer globally, we need to make sure the voices of people affected by TB are at the core of developing person-centered, quality TB care, free from stigma and discrimination, argue a group of TB experts and activists.

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Opinion: WHO numbers underscore urgent need for stronger leadership and ambitious TB recovery plan

According to new estimates from the World Health Organization around 61 000 people died of TB in South Africa in 2020, an increase of around 5% over 2019. That works out to over 1 100 TB deaths in the country every week. We urgently need a transparent TB recovery plan and we need both President Cyril Ramaphosa and Health Minister Joe Phaahla to invest real political capital in the implementation of the plan, the authors argue.

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