HIV is known for its ability to outsmart our immune system’s normal defences. A small number of people living with HIV are however able to generate more effective immune responses to HIV. In this special briefing, Catherine Tomlinson zooms in on broadly neutralising antibodies, the secret sauce in these immune responses.
A groundbreaking project to study potential HIV vaccines in several African countries has been derailed by an abrupt cut in funding from the United States government. As a result, several promising vaccine candidates might not be tested in clinical trials. Catherine Tomlinson reports.
Top South African HIV clinicians are setting their sights on different approaches to finding an HIV vaccine after the “disappointing” news that the Mosaico trial was stopped early because the vaccine did not show any efficacy. The search for an HIV jab now seems set to pivot from vaccines that induce T-cell immunity to ones that induce B-cell immunity. Adele Baleta unpacks what that means and the reasoning behind it.
While progress in the race for effective COVID-19 vaccines has been rapid and impressive, an effective HIV vaccine remains elusive. As part of Spotlight’s World AIDS Day 2020 coverage, Kathryn Cleary asks two of South Africa’s top vaccine researchers to update us on where we are in the race for an HIV vaccine.
The COVID-19 virus is spreading rapidly globally and the race is on for a vaccine to curb the respiratory infection. Adele Baleta unpacks the research and development initiatives underway.
A full version of the special edition of Spotlight will be released during the International AIDS Conference in Durban which starts on 17 July. This is an article which will be published in Spotlight.
