Important TB drug as effective at lower dose, study finds

Important TB drug as effective at lower dose, study finds

The treatment of drug-resistant forms of tuberculosis has been transformed over the last decade with treatment becoming more effective, safer, and treatment duration in many cases dropping to under a year. Even so, treatment can still come with serious side effects and for some, it can still last over a year and a half. In a finding that may help further reduce side effects, new research has found that the dosage of a key drug can be lowered without compromising how well it works. Tiyese Jeranji and Marcus Low report.

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Opinion: Could community health workers be the answer to reducing Tuberculosis stigma?

Opinion: Could community health workers be the answer to reducing Tuberculosis stigma?

Tuberculosis stigma thrives when TB is spoken about in hushed whispers, or behind closed doors. The truth is anyone who breathes can get TB as it is an airborne disease like COVID-19. We can all reduce the harmful effect of TB stigma in our communities by taking part in activities that break down false and unfair attitudes towards people with TB. Community health workers are leading the way and deserve more support, write authors from TB Proof.

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Western Cape to launch COVID-style tuberculosis dashboard

Western Cape to launch COVID-style tuberculosis dashboard

The COVID-19 pandemic caused huge setbacks for the fight against TB. Now, provinces are developing TB catch-up plans. The Western Cape Department of Health will soon launch a TB dashboard as part of its “multi-sectorial TB emergency response plan”. Tiyese Jeranji reports.

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Analysis: We need to do for TB vaccines what we’ve done for COVID-19

Analysis: We need to do for TB vaccines what we’ve done for COVID-19

It is little wonder that some TB vaccine researchers suffer from a rare syndrome that understandably threatens their mental health. Symptoms include frustration, impatience, irritability, seemingly inexplicable rage, and in the least resilient, despair. It’s called VJS or vaccine jealousy syndrome, writes Chris Bateman.

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New HIV/TB plan delayed by a year because of COVID-19

New HIV/TB plan delayed by a year because of COVID-19

South Africa will delay introducing a new HIV and TB plan until 2024, Deputy President David Mabuza revealed on Wednesday. The plan is delayed to allow the country’s HIV and TB responses to recover from COVID-19-related disruptions. Laura Lopez Gonzalez reports for Spotlight.

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XACT III: A trial asking how to take TB tests to the people

XACT III: A trial asking how to take TB tests to the people

Roughly two in five people newly ill with TB worldwide are never diagnosed. In South Africa, this amounts to about 120 000 to 160 000 people per year. A large new study called XACT III is testing ways in which more people can be diagnosed and started on TB treatment more quickly. Tiyese Jeranji reports.

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For next pandemic we need vaccines in 100 days, says expert

For next pandemic we need vaccines in 100 days, says expert

Developing COVID-19 vaccines in less than a year came from repurposing multiple, decade-old vaccine research platforms, but too many lives were lost, and a new goal of developing vaccines in 100 days is needed to counter the next global pathogen, experts say.

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Opinion: Six ways clinics can help turn the tide on TB infection

Opinion: Six ways clinics can help turn the tide on TB infection

Six simple interventions are at the heart of how clinics can be part of turning the tide on TB infection. By following a checklist of good practice, clinics can be safer for patients and staff. However, most clinics are failing to implement enough of these measures, putting people at risk of getting TB while waiting at the clinic, argues representatives from the community clinic monitoring group Ritshidze.

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After setbacks, rollout of new TB prevention pills to start in six districts

After setbacks, rollout of new TB prevention pills to start in six districts

After various delays and setbacks, a new, less toxic, short-course tuberculosis preventive therapy called 3HP is finally being launched in six districts in South Africa. Tiyese Jeranji reports.

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SA piloting mobile X-rays to improve TB detection

SA piloting mobile X-rays to improve TB detection

South Africa’s first National Tuberculosis Prevalence Survey found that many people without TB symptoms nevertheless have TB disease that can be detected using chest X-rays. Accordingly, new mobile X-ray screening programmes are being piloted in a number of provinces. Tiyese Jeranji reports.

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In-depth: SA at cutting edge of TB vaccine research

In-depth: SA at cutting edge of TB vaccine research

It is a hundred years since the BCG vaccine, the only registered vaccine proven to offer some protection against tuberculosis (TB), was first used in people. Now researchers in South Africa are at the forefront of clinical trials testing experimental new TB vaccines. Adele Baleta reports.

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Opinion: World TB Day – let’s seize this moment to change the status quo

Opinion: World TB Day – let’s seize this moment to change the status quo

Like with SARS-CoV2, we need to rapidly implement and scale-up effective tuberculosis (TB) prevention interventions, while remaining adaptive to prevailing needs across the country. If we choose to pursue this more deliberate approach to TB prevention in South Africa, World TB Day will no longer be an admission of insufficient progress, but a celebration of defeating our long-standing battle with this curable disease, writes Dr Kavindhran Velen and Professor Salome Charalambous.

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