The treatment of drug-resistant forms of tuberculosis has been transformed over the last decade with treatment becoming more effective, safer, and treatment duration in many cases dropping to under a year. Even so, treatment can still come with serious side effects and for some, it can still last over a year and a half. In a finding that may help further reduce side effects, new research has found that the dosage of a key drug can be lowered without compromising how well it works. Tiyese Jeranji and Marcus Low report.
Tuberculosis stigma thrives when TB is spoken about in hushed whispers, or behind closed doors. The truth is anyone who breathes can get TB as it is an airborne disease like COVID-19. We can all reduce the harmful effect of TB stigma in our communities by taking part in activities that break down false and unfair attitudes towards people with TB. Community health workers are leading the way and deserve more support, write authors from TB Proof.
After various delays and setbacks, a new, less toxic, short-course tuberculosis preventive therapy called 3HP is finally being launched in six districts in South Africa. Tiyese Jeranji reports.
South Africa’s first National Tuberculosis Prevalence Survey found that many people without TB symptoms nevertheless have TB disease that can be detected using chest X-rays. Accordingly, new mobile X-ray screening programmes are being piloted in a number of provinces. Tiyese Jeranji reports.
It is a hundred years since the BCG vaccine, the only registered vaccine proven to offer some protection against tuberculosis (TB), was first used in people. Now researchers in South Africa are at the forefront of clinical trials testing experimental new TB vaccines. Adele Baleta reports.
Treating highly drug-resistant forms of tuberculosis can take anything from nine to 24 months and patients have to contend with various unpleasant, and sometimes dangerous, side effects. A new six-month regimen made up of just three drugs that will be offered to 400 patients in South Africa might offer a better solution for some. Tiyese Jeranji reports.
From March to July this year, the Gauteng Department of Health recorded 57 848 TB tests – a decrease of about 30 000 tests compared to the same period last year. The province performed better with HIV testing, although the HIV response has faltered in other areas. Melissa Javan makes sense of the province’s numbers and speaks to activists and community health workers about the impact of lockdown on their services and plans to get things back on track.
Children shoulder approximately 12% of the global TB burden, and this proportion is likely higher in high TB burden countries. In South Africa, up to 30 000 children develop TB each year. Tiyese Jeranji spoke to TB expert, Dr Megan Palmer from Brooklyn Chest Hospital about treatment challenges and how to improve TB detection and treatment outcomes in children.
Numbers from the National Institute of Communicable Disease and from some provinces show that TB diagnoses have dropped dramatically in 2020 – likely due to COVID-19 and the related lockdown. The Eastern Cape Department of Health has however declined to share information on the TB situation in the province and their catch-up plans. Some activists are concerned about the situation. Luvuyo Mehlwana reports.
A World Health Organization report published last week showed more people are falling ill with tuberculosis in South Africa than previously thought – but also that the country’s treatment success rate for dangerous drug-resistant forms of the disease have improved. Amy Green asks what’s behind these numbers.
People with COVID-19 and people with tuberculosis (TB) can experience similar symptoms such as coughing and breathing difficulties as both diseases affect the lungs. Exactly how these diseases affect the lungs, however, differs. Tiyese Jeranji spoke to a leading South African pulmonologist to learn more.
Some tuberculosis patients in South Africa are still required to take their pills in front of a healthcare worker or family member. Is this a justified means of ensuring people take their medicine, or is it an invasion of personal autonomy? Elri Voigt asked local TB experts.